引用本文:
Li Yan Sun, Zhen Liang Liu, Tao Zhang, Shu Bin Niu, Zun Tian Zhao. Three antibacterial naphthoquinone analogues from cultured mycobiont of lichen Astrothelium sp[J]. Chinese Chemical Letters,
2010, 21(7): 842-845.
doi:
10.1016/j.cclet.2010.03.024
Citation: Li Yan Sun, Zhen Liang Liu, Tao Zhang, Shu Bin Niu, Zun Tian Zhao. Three antibacterial naphthoquinone analogues from cultured mycobiont of lichen Astrothelium sp[J]. Chinese Chemical Letters, 2010, 21(7): 842-845. doi: 10.1016/j.cclet.2010.03.024
Citation: Li Yan Sun, Zhen Liang Liu, Tao Zhang, Shu Bin Niu, Zun Tian Zhao. Three antibacterial naphthoquinone analogues from cultured mycobiont of lichen Astrothelium sp[J]. Chinese Chemical Letters, 2010, 21(7): 842-845. doi: 10.1016/j.cclet.2010.03.024
Three antibacterial naphthoquinone analogues from cultured mycobiont of lichen Astrothelium sp
摘要:
A new naphthoquinone compound named 7-hydroxyl-8-methoxyltrypethelone 3 together with two known compounds trypethelone 1 and trypethelone methyl ether 2 was isolated from cultured mycobiunt of Astrothelium sp.The structures were elucidated by 1D and 2D NMR spectroscopic analysis as well as comparison with those reported in literatures.Compound 1 displayed significant antibacterial activity against Bacillus subtilis (ATCC 6633),and showed modest antibacterial activity against Staphylococcus aureus col (MRSA) (CGMCC 1.2465),while compounds 2 and 3 showed modest antibacterial activity against Enterococcus faecalis 850E (CGMCC 1.2135)and S.aureus col (MRSA) (CGMCC 1.2465).
English
Three antibacterial naphthoquinone analogues from cultured mycobiont of lichen Astrothelium sp
Abstract:
A new naphthoquinone compound named 7-hydroxyl-8-methoxyltrypethelone 3 together with two known compounds trypethelone 1 and trypethelone methyl ether 2 was isolated from cultured mycobiunt of Astrothelium sp.The structures were elucidated by 1D and 2D NMR spectroscopic analysis as well as comparison with those reported in literatures.Compound 1 displayed significant antibacterial activity against Bacillus subtilis (ATCC 6633),and showed modest antibacterial activity against Staphylococcus aureus col (MRSA) (CGMCC 1.2465),while compounds 2 and 3 showed modest antibacterial activity against Enterococcus faecalis 850E (CGMCC 1.2135)and S.aureus col (MRSA) (CGMCC 1.2465).
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Key words:
- Astrothelium sp.
- / Lichen
- / Mycobiont
- / 7-Hydroxyl-8-methoxyltrypethelone
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