Citation: Pei Liu, Li Liu, Yu Ping Tang, Jin Ao Duan, Nian Yun Yang. A new cerebroside and its anti-proliferation effect on VSMCs from the radix of Cyperus rotundus L.[J]. Chinese Chemical Letters, ;2010, 21(5): 606-609. doi: 10.1016/j.cclet.2010.01.012 shu

A new cerebroside and its anti-proliferation effect on VSMCs from the radix of Cyperus rotundus L.

Jiangsu Key Laboratory for TCM Formulae Research, Nanjing University of Chinese Medicine, Nanjing 210046, China

Received Date: 22 September 2009

Fund Project: This research was supported by 2006 Great Basic Science Research Project of Jiangsu College and University (No. 06KJA36022). We also thank Dr. Dong Jun Chen, Dr. Er Xin Shang, Dr. Jun Sun, Dr. Shu Lan Su and Bin Bin Huang for other helpful assistance.

A new cerebroside, 1-O-(β-D-glucopyranosyloxy)-(2S,3R,4E,8Z)-2- [(2'R)-2'-hydroxylignoceranoylainino]-4,8-tetradecene-3-diol was isolated from the 60% EtOH extract of traditional Chinese medical plant Cyperus rotundus L. Its structure was determined on the basis of spectroscopic data. This new compound showed anti-proliferation effect on vascular smooth muscle cells (VSMCs).
- Cyperus rotundus,
- Cerebroside,
- Anti-proliferation effect,
- Vascular smooth muscle cells (VSMCs)
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