Citation: Liang Zhang, Wen Bo Ding, Yong Ping Yu, Hong Bin Zou. Direct asymmetric aldol reaction using MBHA resin-supported peptide containing L-proline unit[J]. Chinese Chemical Letters, ;2009, 20(9): 1065-1067. doi: 10.1016/j.cclet.2009.04.034 shu

Direct asymmetric aldol reaction using MBHA resin-supported peptide containing L-proline unit

Institute of Materia Medica, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China

Received Date: 11 February 2009

MBHA resin-supported tripeptide catalyst system containing L-proline unit has been developed for use in the direct asymmetric aldol reaction of acetone and aldehydes, which afford the corresponding products with satisfactory isolated yields and enantiomeric excesses.
- Direct asymmetric aldol reaction,
- MBHA resin-supported peptide,
- L-Proline;"Tea-bag"methodology
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