引用本文:
Yu Lang Chi, Hui Ye Zhang, Jing Hua Xue, Jing Hao, Mei Fang Liu, Xiao Yi Wei. N2-(1-Methoxycarbonylethyl) guanosine, a new nucleoside coupled with an amino acid derivative from Amanita exitialis[J]. Chinese Chemical Letters,
2009, 20(7): 830-832.
doi:
10.1016/j.cclet.2009.02.008
Citation: Yu Lang Chi, Hui Ye Zhang, Jing Hua Xue, Jing Hao, Mei Fang Liu, Xiao Yi Wei. N2-(1-Methoxycarbonylethyl) guanosine, a new nucleoside coupled with an amino acid derivative from Amanita exitialis[J]. Chinese Chemical Letters, 2009, 20(7): 830-832. doi: 10.1016/j.cclet.2009.02.008
Citation: Yu Lang Chi, Hui Ye Zhang, Jing Hua Xue, Jing Hao, Mei Fang Liu, Xiao Yi Wei. N2-(1-Methoxycarbonylethyl) guanosine, a new nucleoside coupled with an amino acid derivative from Amanita exitialis[J]. Chinese Chemical Letters, 2009, 20(7): 830-832. doi: 10.1016/j.cclet.2009.02.008
N2-(1-Methoxycarbonylethyl) guanosine, a new nucleoside coupled with an amino acid derivative from Amanita exitialis
摘要:
A new purine nucleoside coupled with an amino acid derivative, N2-(1-methoxycarbonylethyl) guanosine 1, along with β-carbolineand russulaceramide was isolated from the fruiting bodies of Amanita exitialis, a newly described poisonous mushroom.Its structure was elucidated by spectroscopic methods. This is the first report of naturally occurring nucleosides in which an α-amino acid derivative is bonded through its α-amino nitrogen to a nucleobase aglycone by a C-N bond. The new compound was found to be toxic in brine shrimp lethality test (BST).
English
N2-(1-Methoxycarbonylethyl) guanosine, a new nucleoside coupled with an amino acid derivative from Amanita exitialis
Abstract:
A new purine nucleoside coupled with an amino acid derivative, N2-(1-methoxycarbonylethyl) guanosine 1, along with β-carbolineand russulaceramide was isolated from the fruiting bodies of Amanita exitialis, a newly described poisonous mushroom.Its structure was elucidated by spectroscopic methods. This is the first report of naturally occurring nucleosides in which an α-amino acid derivative is bonded through its α-amino nitrogen to a nucleobase aglycone by a C-N bond. The new compound was found to be toxic in brine shrimp lethality test (BST).
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Key words:
- N2-(1-Methoxycarbonylethyl)guanosine
- / Guanosine
- / Purine alkaloid
- / Nucleoside
- / Amanita
- / Amanita exitialis
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