Citation: Xiang Hong Huang, Xu Feng Lin, Su Qin Chen, Yan Guang Wang. Total synthesis of glypetelotine[J]. Chinese Chemical Letters, ;2009, 20(6): 643-644. doi: 10.1016/j.cclet.2009.02.005 shu

Total synthesis of glypetelotine

a College of Biology and Environmental Engineering, Zhejiang Shuren University, Hangzhou 310015, PR China;
b Department of Chemistry, Zhejiang University, Hangzhou 310027, PR China;
c College of Chemical and Material Engineering, Wenzhou University, Wenzhou 325027, PR China

Received Date: 27 October 2008

Fund Project: This work was financially supported by the Natural Science Foundation of Zhejiang Province (No.Y404347).

A total synthesis of glypetelotine, the first sulphur-containing indole alkaloid from the leaf extracts of Glycosmis petelotii collected in the north of Vietnam, was described from indole through 6 steps. The structure of the glypetelotine was confirmed by IR, ¹H NMR, ₁₃C NMR and MS analysis. The spectral data of synthetic compound was identical with those of natural compound.
- Sulphur-containing alkaloid,
- Glypetelotine,
- Total synthesis,
- Indole
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