One-step synthesis of inherently chiral p-tert-butylcalix[4]azacrown

Shao Yong Li Bei Sun Zhi Chao Xiao Ming Hui Huang Wei Xue Xie Jun Min Liu

引用本文: Shao Yong Li,  Bei Sun,  Zhi Chao Xiao,  Ming Hui Huang,  Wei Xue Xie,  Jun Min Liu. One-step synthesis of inherently chiral p-tert-butylcalix[4]azacrown[J]. Chinese Chemical Letters, 2009, 20(6): 640-642. doi: 10.1016/j.cclet.2009.01.019 shu
Citation:  Shao Yong Li,  Bei Sun,  Zhi Chao Xiao,  Ming Hui Huang,  Wei Xue Xie,  Jun Min Liu. One-step synthesis of inherently chiral p-tert-butylcalix[4]azacrown[J]. Chinese Chemical Letters, 2009, 20(6): 640-642. doi: 10.1016/j.cclet.2009.01.019 shu

One-step synthesis of inherently chiral p-tert-butylcalix[4]azacrown

  • 基金项目:

    We thank the Science Foundation of Tianjin Medical University (No.2006x9d2) and the National Natural Science Foundation of China, the Major State Basic Research Development Program of China (No.20502008) for financial support.

摘要: A one-step procedure is developed to synthesize inherently chiral p-tert-butylcalix[4]azacrown 1 through etherification between p-tert-butylcalix[4]arene and compound 3, which can be amplified to efficiently prepare more inherently chiral calix[4]arenes in ABHH substitution pattern.

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  • 收稿日期:  2008-11-10
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