引用本文:
Ping Zhang, Lan Zhi Wang, Hui Shu Wu, Jia Ming Lan, Yuan Li, Yong Xiang Wang. The synthesis and biological evaluation of a series of novel 2-COOC2H5/COONa substituted 1,5-benzothiazepine derivatives as antimicrobial agents[J]. Chinese Chemical Letters,
2009, 20(6): 660-662.
doi:
10.1016/j.cclet.2009.01.003
Citation: Ping Zhang, Lan Zhi Wang, Hui Shu Wu, Jia Ming Lan, Yuan Li, Yong Xiang Wang. The synthesis and biological evaluation of a series of novel 2-COOC2H5/COONa substituted 1,5-benzothiazepine derivatives as antimicrobial agents[J]. Chinese Chemical Letters, 2009, 20(6): 660-662. doi: 10.1016/j.cclet.2009.01.003
Citation: Ping Zhang, Lan Zhi Wang, Hui Shu Wu, Jia Ming Lan, Yuan Li, Yong Xiang Wang. The synthesis and biological evaluation of a series of novel 2-COOC2H5/COONa substituted 1,5-benzothiazepine derivatives as antimicrobial agents[J]. Chinese Chemical Letters, 2009, 20(6): 660-662. doi: 10.1016/j.cclet.2009.01.003
The synthesis and biological evaluation of a series of novel 2-COOC2H5/COONa substituted 1,5-benzothiazepine derivatives as antimicrobial agents
摘要:
A series of novel 1,5-benzothiazepine derivatives containing COOC2H5/COONa groups at the C(2)-position were synthesized and evaluated for their antifungal and antibacterial activities by both disc diffusion and minimal inhibition concentration (MIC) methods. Most of the compounds have been shown to have moderate to good antibacterial activity against S. aureus, S. epidermidis and excellent antifungal activity against C. albicans.
English
The synthesis and biological evaluation of a series of novel 2-COOC2H5/COONa substituted 1,5-benzothiazepine derivatives as antimicrobial agents
Abstract:
A series of novel 1,5-benzothiazepine derivatives containing COOC2H5/COONa groups at the C(2)-position were synthesized and evaluated for their antifungal and antibacterial activities by both disc diffusion and minimal inhibition concentration (MIC) methods. Most of the compounds have been shown to have moderate to good antibacterial activity against S. aureus, S. epidermidis and excellent antifungal activity against C. albicans.
-
Key words:
- 1,5-Benzothiazepine
- / Antifungal
- / Antibacterial activities
扫一扫看文章
计量
- PDF下载量: 2
- 文章访问数: 1737
- HTML全文浏览量: 49
下载:
