Citation:
Yu Juan Gan, Wen Li Mei, You Xing Zhao, Hao Fu Dai. A new cytotoxic cardenolide from the latex of Antiaris toxicaria[J]. Chinese Chemical Letters,
;2009, 20(4): 450-452.
doi:
10.1016/j.cclet.2008.12.043
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A new cardenolide, toxicarioside E (1), was isolated from the latex of Antiaris toxicaria (Pers.) Lesch (Moraceae). Its structure was elucidated on the basis of spectral data and chemical evidence. Compound 1 showed significant cytotoxicity against K562 and SGC-7901 cell lines in vitro by MTT method with the IC50 value of 0.026 and 0.027μg/mL, respectively.
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Keywords:
- Antiaris toxicaria,
- Moraceae,
- Toxicarioside E,
- Cardenolide,
- Cytotoxicity
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