Citation: Katayoun Marjani, Maryam Asgari, Akram Ashouri, Gholam Hossein Mahdavinia, Hossien Abbastabar Ahangar. Microwave-assisted aldol condensation of benzil with ketones[J]. Chinese Chemical Letters, ;2009, 20(4): 401-403. doi: 10.1016/j.cclet.2008.12.036 shu

Microwave-assisted aldol condensation of benzil with ketones

a Faculty of Chemistry, Tarbiat Moallem University, P. O. Box 15614, Tehran, Iran;
b Department of Chemistry, Islamic Azad University-Marvdasht Branch, Marvdasht, Iran

Received Date: 9 September 2008

Fund Project: We are grateful to Tarbiat Moallem University Research Council for partial support of this work.

Under microwave irradiation, the corresponding hydroxycyclopentenones were prepared in high yields by the cross-aldol reactions of benzil with various ketones. When the reactions were performed in various solvents under classical heating for a long time, they produced the products in relatively low yields.
- Benzil,
- Microwave irradiation,
- Cross-aldol reaction,
- Hydroxycyclopentenones
1. [1]
  Jian Feng Zhou , Gui Xia Gong , Kun Bao Shi , San Jun Zhi . Catalyst-free and solvent-free method for the synthesis of quinoxalines under microwave irradiation. Chinese Chemical Letters, 2009, 20(6): 672-675. doi: 10.1016/j.cclet.2009.02.007
2. [2]
  Jian Feng Zhou , Gui Xia Gong , Hui Qin Zhu , Feng Xia Zhu . Solvent-free and catalyst-free method for the synthesis of 2,4,5-triarylimidazoles under microwave irradiation. Chinese Chemical Letters, 2009, 20(10): 1198-1200. doi: 10.1016/j.cclet.2009.05.027
3. [3]
  Xi Cun Wang , Hai Peng Gong , Zheng Jun Quan , Lei Li , He Lin Ye . PEG-400 as an efficient reaction medium for the synthesis of 2,4,5-triaryl-1H-imidazoles and 1,2,4,5-tetraaryl-1H-imidazoles. Chinese Chemical Letters, 2009, 20(1): 44-47. doi: 10.1016/j.cclet.2008.10.005
4. [4]
  Hua Cheng , Qiong-You Wu , Fan Han , Guang-Fu Yang . Efficient synthesis of 4-substituted pyrazole via microwave-promoted Suzuki cross-coupling reaction. Chinese Chemical Letters, 2014, 25(05): 705-709. doi: 10.1016/j.cclet.2014.03.013
5. [5]
  Mohammad Javaherian , Foad Kazemi , Masoumeh Ghaemi . A dicationic, podand-like, ionic liquid water system accelerated copper-catalyzed azide-alkyne click reaction. Chinese Chemical Letters, 2014, 25(12): 1643-1647. doi: 10.1016/j.cclet.2014.09.005
6. [6]
  Jaiprakash N. Sangshetti , Nagnnath D. Kokare , Sandeep A. Kotharkar , Devanand B. Shinde . ZrOC1₂·8H₂O catalyzed one-pot synthesis of 2,4,5-triaryl-1H-imidazoles and substituted 1,4-di(4,5-diphenylimidazolyl)benzene. Chinese Chemical Letters, 2008, 19(7): 762-766. doi: 10.1016/j.cclet.2008.05.007
7. [7]
  Yu Jing Lu , Ning Sun , Zhi Shu Huang , Lian Quan Gu . A rapid and efficient synthesis of indoloquinolinone and its analogues under microwave irradiation. Chinese Chemical Letters, 2008, 19(5): 518-520. doi: 10.1016/j.cclet.2008.03.028
8. [8]
  Xiong Wen Ye , Yu Ping Zhang , Ling Bo Qu , Li Qun Fan , Bo Li . Novel preparation of organic polymer-based monolithic column by microwave irradiation. Chinese Chemical Letters, 2007, 18(11): 1399-1402. doi: 10.1016/j.cclet.2007.09.027
9. [9]
  Xue Sen Fan , Xia Wang , Xiao Yan Li . An unexpected reaction of cyanothioacetamide:Novel preparation of pyrazolo[3,4-b]-pyridine derivatives under. Chinese Chemical Letters, 2008, 19(6): 643-646. doi: 10.1016/j.cclet.2008.03.005
10. [10]
  Xin-Ping Ouyang , Chun-Lei Liu , Yu-Xia Pang , Xue-Qing Qiu . Synthesis of a trimeric lignin model compound composed of α-O-4 and β-O-4 linkages under microwave irradiation. Chinese Chemical Letters, 2013, 24(12): 1091-1094.
11. [11]
  Rui Chen , Jian Yuan Hao , Cheng Dong Xiong , Xian Mo Deng . Rapid synthesis of biodegradable poly(epsilon-caprolactone-co-p-dioxanone)random copolymers under microwave irradiation. Chinese Chemical Letters, 2010, 21(2): 249-252. doi: 10.1016/j.cclet.2009.10.022
12. [12]
  Feng Zhang , Ya Zhuo Li , Da Wei Gao , Ji Kui Sun , Yu Min Zhang . Synthesis of diethers derived from furoin by phase transfer catalysis under microwave irradiation. Chinese Chemical Letters, 2007, 18(7): 791-794. doi: 10.1016/j.cclet.2007.05.030
13. [13]
  Lan Ying WANG , Xiao Gang ZHANG , Ying Qi JIA , Zu Xun ZHANG . Solvent-free Rapid Synthesis of Styryl Dyes with Benzimidazole Nucleus Using Microwave Irradiation. Chinese Chemical Letters, 2003, 14(11): 1116-1118.
14. [14]
  Long-Qiang Xiao , Xiang-Xiang Jia , Li-Qiong Liao , Li-Jian Liu . Synthesis of azo-incorporated copolymers by C1/N2C1 copolymerization under microwave irradiation. Chinese Chemical Letters, 2014, 25(12): 1601-1606. doi: 10.1016/j.cclet.2014.09.009
15. [15]
  Zhi Gang Zhao , Xing Li Liu , Cai E. Zhou . K₂CO₃ catalyzed solvent-free synthesis of molecular tweezers containing chiral unsymmetrical urea unit under microwave irradiation. Chinese Chemical Letters, 2007, 18(9): 1067-1070. doi: 10.1016/j.cclet.2007.06.030
16. [16]
  Xiao Hui ZHANG , Da Bin GAO , Ming GUO , Shan Zhen YAN . Synthesis of α,β-Unsaturated Ketones using Potassium fluoridealumina Catalyst by Microwave Irradiation. Chinese Chemical Letters, 1998, 9(6): 521-522.
17. [17]
  A. Davoodnia , M. Roshani , S.H. Malaeke , M. Bakavoli . A rapid synthesis of isoxazolo[5,4-d]pyrimidin-4(5H)-ones under microwave irradiation with solid acid catalysis in solvent-free conditions. Chinese Chemical Letters, 2008, 19(5): 525-528. doi: 10.1016/j.cclet.2008.01.037
18. [18]
  Ratnadeep S. Joshi , Priyanka G. Mandhane , Mohammad U. Shaikh , Rajesh P. Kale , Charansingh H. Gill . Potassium dihydrogen phosphate catalyzed one-pot synthesis of 2,4,5-triaryl-1H-imidazoles. Chinese Chemical Letters, 2010, 21(4): 429-432. doi: 10.1016/j.cclet.2009.11.012
19. [19]
  Hui Zhu , Ri Fang Yang , Liu Hong Yun , Jin Li . Facile and efficient synthesis of quinoline-4-carboxylic acids under microwave irradiation. Chinese Chemical Letters, 2010, 21(1): 35-38. doi: 10.1016/j.cclet.2009.09.012
20. [20]
  Hai Qian , Wei Chen , Jin Pei Zhou , Wen Long Huang , Hui Bin Zhang , Jing Jin . Total synthesis of endothelin 1 by microwave-assisted solid phase method. Chinese Chemical Letters, 2010, 21(4): 388-390. doi: 10.1016/j.cclet.2009.12.016

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