引用本文:
Zhao Hui Wang, Wen Yun Li, Fu Long Li, Lei Zhang, Wei Yi Hua, Jing Cai Cheng, Qi Zheng Yao. Synthesis and antitumor activity of 7-azaindirubin[J]. Chinese Chemical Letters,
2009, 20(5): 542-544.
doi:
10.1016/j.cclet.2008.12.011
Citation: Zhao Hui Wang, Wen Yun Li, Fu Long Li, Lei Zhang, Wei Yi Hua, Jing Cai Cheng, Qi Zheng Yao. Synthesis and antitumor activity of 7-azaindirubin[J]. Chinese Chemical Letters, 2009, 20(5): 542-544. doi: 10.1016/j.cclet.2008.12.011
Citation: Zhao Hui Wang, Wen Yun Li, Fu Long Li, Lei Zhang, Wei Yi Hua, Jing Cai Cheng, Qi Zheng Yao. Synthesis and antitumor activity of 7-azaindirubin[J]. Chinese Chemical Letters, 2009, 20(5): 542-544. doi: 10.1016/j.cclet.2008.12.011
Synthesis and antitumor activity of 7-azaindirubin
摘要:
Twenty 7-azaindirubin derivatives were designed and synthesized. Their antitumor activities were evaluated in vitro against DU145 cell line. The pharmacological results showed that most of the prepared compounds displayed the excellent activity.Compound 18 exhibited the most potent antitumor activity among the tested compounds.
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关键词:
- 7-Azaindirubin
- / Synthesis
- / Antitumor activity
English
Synthesis and antitumor activity of 7-azaindirubin
Abstract:
Twenty 7-azaindirubin derivatives were designed and synthesized. Their antitumor activities were evaluated in vitro against DU145 cell line. The pharmacological results showed that most of the prepared compounds displayed the excellent activity.Compound 18 exhibited the most potent antitumor activity among the tested compounds.
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Key words:
- 7-Azaindirubin
- / Synthesis
- / Antitumor activity
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