Chelerythrine chloride binding of guanosine in aqueous solution

引用本文: Fan Liu, Jian Bin Zhang, Zheng Fu Zhang, Xiao Yan Zhang, Zuo Peng Du, Xiong Hui Wei. Chelerythrine chloride binding of guanosine in aqueous solution[J]. Chinese Chemical Letters, 2009, 20(1): 66-70. doi: 10.1016/j.cclet.2008.10.023 shu

Citation: Fan Liu, Jian Bin Zhang, Zheng Fu Zhang, Xiao Yan Zhang, Zuo Peng Du, Xiong Hui Wei. Chelerythrine chloride binding of guanosine in aqueous solution[J]. Chinese Chemical Letters, 2009, 20(1): 66-70. doi: 10.1016/j.cclet.2008.10.023 shu

Chelerythrine chloride binding of guanosine in aqueous solution

a College of Chemical Engineering, Inner Mongolia University of Technology, Huhhot 010051, China;
b Department of Applied Chemistry, College of Chemistry & Molecular Engineering, Peking University, Beijing 100190, China
基金项目:
This project is financed by Jiangxi Boyuan Industry Co., Ltd. (Jiangxi province, China). Thanks to Professor Wenting Hua and Professor Hongcheng Gao (Peking University, China) for their suggestions on the interaction mechanism of CHE with guanosine.

摘要: In this work, the interaction between chelerythrine (CHE) and guanosine is studied usingUV-vis and fluorescence measurements at various temperatures. The UV-vis spectra show that the increasing guanosine concentrations result in the decreasing absorption intensity and red shift of CHE E absorption band (267 nm). The fluorescence spectra are fitted to linear analysis, yielding a binding constant of 1.04×10⁴ L/mol at 298.15 K of CHE with guanosine. Besides, with △_rH_m^Θ=-8.26 kJ=mol, △_rG_m^Θ=-22.90 kJ=mol,and △_rS_m^Θ=-49.38 J/(molK)the interaction should be entropy-driven and exterothermic.

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English

Chelerythrine chloride binding of guanosine in aqueous solution

a College of Chemical Engineering, Inner Mongolia University of Technology, Huhhot 010051, China;
b Department of Applied Chemistry, College of Chemistry & Molecular Engineering, Peking University, Beijing 100190, China
Received Date: 28 August 2008
Fund Project:
This project is financed by Jiangxi Boyuan Industry Co., Ltd. (Jiangxi province, China). Thanks to Professor Wenting Hua and Professor Hongcheng Gao (Peking University, China) for their suggestions on the interaction mechanism of CHE with guanosine.

Abstract: In this work, the interaction between chelerythrine (CHE) and guanosine is studied usingUV-vis and fluorescence measurements at various temperatures. The UV-vis spectra show that the increasing guanosine concentrations result in the decreasing absorption intensity and red shift of CHE E absorption band (267 nm). The fluorescence spectra are fitted to linear analysis, yielding a binding constant of 1.04×10⁴ L/mol at 298.15 K of CHE with guanosine. Besides, with △_rH_m^Θ=-8.26 kJ=mol, △_rG_m^Θ=-22.90 kJ=mol,and △_rS_m^Θ=-49.38 J/(molK)the interaction should be entropy-driven and exterothermic.

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Chelerythrine chloride binding of guanosine in aqueous solution

English

Chelerythrine chloride binding of guanosine in aqueous solution

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Chelerythrine chloride binding of guanosine in aqueous solution

English

Chelerythrine chloride binding of guanosine in aqueous solution

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

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