引用本文:
Bin Wu, Li Zhou, Hui Hui Cai. Synthesis and neuroprotective properties of novel cinnamide dertvatives[J]. Chinese Chemical Letters,
2008, 19(10): 1163-1166.
doi:
10.1016/j.cclet.2008.06.052
Citation: Bin Wu, Li Zhou, Hui Hui Cai. Synthesis and neuroprotective properties of novel cinnamide dertvatives[J]. Chinese Chemical Letters, 2008, 19(10): 1163-1166. doi: 10.1016/j.cclet.2008.06.052
Citation: Bin Wu, Li Zhou, Hui Hui Cai. Synthesis and neuroprotective properties of novel cinnamide dertvatives[J]. Chinese Chemical Letters, 2008, 19(10): 1163-1166. doi: 10.1016/j.cclet.2008.06.052
Synthesis and neuroprotective properties of novel cinnamide dertvatives
摘要:
A new series of compounds (E)-1-(4-(bis-arylmethyl)piperazin-l-y1)-3-arylprop-2-en-1-one(1a-r),have been synthesized and their structures were confirmed by ESI-MS and 1H NMR.The preliminary pharmacological screening showed that some of these compounds had similar neuroprotective effects with Edaravone.
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关键词:
- Cinnamide derivatives
- / Synthesis
- / Neuroprotective
- / Fdaravone
English
Synthesis and neuroprotective properties of novel cinnamide dertvatives
Abstract:
A new series of compounds (E)-1-(4-(bis-arylmethyl)piperazin-l-y1)-3-arylprop-2-en-1-one(1a-r),have been synthesized and their structures were confirmed by ESI-MS and 1H NMR.The preliminary pharmacological screening showed that some of these compounds had similar neuroprotective effects with Edaravone.
-
Key words:
- Cinnamide derivatives
- / Synthesis
- / Neuroprotective
- / Fdaravone
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