Polyethylene glycol (PEG) as a benign solvent for Knoevenagel condensation

Yang Liu Jun Liang Xiu Hong Liu Ji Cai Fan Zhi Cai Shang

引用本文: Yang Liu,  Jun Liang,  Xiu Hong Liu,  Ji Cai Fan,  Zhi Cai Shang. Polyethylene glycol (PEG) as a benign solvent for Knoevenagel condensation[J]. Chinese Chemical Letters, 2008, 19(9): 1043-1046. doi: 10.1016/j.cclet.2008.06.016 shu
Citation:  Yang Liu,  Jun Liang,  Xiu Hong Liu,  Ji Cai Fan,  Zhi Cai Shang. Polyethylene glycol (PEG) as a benign solvent for Knoevenagel condensation[J]. Chinese Chemical Letters, 2008, 19(9): 1043-1046. doi: 10.1016/j.cclet.2008.06.016 shu

Polyethylene glycol (PEG) as a benign solvent for Knoevenagel condensation

摘要: The Knoevenagel condensation of aromatic aldehydes with active methylene compound proceeded efficiently in polyethylene glycol at room temperature with L-proline as catalyst. The yield is high and the products had E-isomer dominantly. Polyethylene glycol containing L-proline could be recycled and reused for several times without noticeably decreasing in productivity.

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  • 收稿日期:  2008-03-19
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