引用本文:
Hui Hui Li, Gu Yuan. Investigation of formation of dimeric G-quadruplex of HIV-1 integrase inhibitor by nuclear magnetic resonance[J]. Chinese Chemical Letters,
2008, 19(9): 1108-1110.
doi:
10.1016/j.cclet.2008.06.010
Citation: Hui Hui Li, Gu Yuan. Investigation of formation of dimeric G-quadruplex of HIV-1 integrase inhibitor by nuclear magnetic resonance[J]. Chinese Chemical Letters, 2008, 19(9): 1108-1110. doi: 10.1016/j.cclet.2008.06.010
Citation: Hui Hui Li, Gu Yuan. Investigation of formation of dimeric G-quadruplex of HIV-1 integrase inhibitor by nuclear magnetic resonance[J]. Chinese Chemical Letters, 2008, 19(9): 1108-1110. doi: 10.1016/j.cclet.2008.06.010
Investigation of formation of dimeric G-quadruplex of HIV-1 integrase inhibitor by nuclear magnetic resonance
摘要:
In this research, an unusually dimeric G-quadruplex of d(GGGTGGGTGGGTGGGT) (Sl), the potent nanomolar HIV-1 integrase inhibitor, was detected by nuclear magnetic resonance (NMR). This result has been confirmed by electrospray ionization mass spectrometry (ESI-MS) and circular dichroism (CD).
English
Investigation of formation of dimeric G-quadruplex of HIV-1 integrase inhibitor by nuclear magnetic resonance
Abstract:
In this research, an unusually dimeric G-quadruplex of d(GGGTGGGTGGGTGGGT) (Sl), the potent nanomolar HIV-1 integrase inhibitor, was detected by nuclear magnetic resonance (NMR). This result has been confirmed by electrospray ionization mass spectrometry (ESI-MS) and circular dichroism (CD).
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Key words:
- G-quadruplex
- / HIV-I integrase inhibitor
- / Nuclear magnetic resonance
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