The synthesis and cytotoxic activity of novel organogermanium sesquioxides with anthraquinone or naphthalene moiety

Guo Qiang Shangguan Lun Liang Huang Xiao Gang Qu

引用本文: Guo Qiang Shangguan,  Lun Liang Huang,  Xiao Gang Qu. The synthesis and cytotoxic activity of novel organogermanium sesquioxides with anthraquinone or naphthalene moiety[J]. Chinese Chemical Letters, 2007, 18(11): 1347-1350. doi: 10.1016/j.cclet.2007.09.029 shu
Citation:  Guo Qiang Shangguan,  Lun Liang Huang,  Xiao Gang Qu. The synthesis and cytotoxic activity of novel organogermanium sesquioxides with anthraquinone or naphthalene moiety[J]. Chinese Chemical Letters, 2007, 18(11): 1347-1350. doi: 10.1016/j.cclet.2007.09.029 shu

The synthesis and cytotoxic activity of novel organogermanium sesquioxides with anthraquinone or naphthalene moiety

摘要: Four novel organogermanium sesquioxides with anthraquinone or naphthalene moiety were synthesized. The structures were characterized by IR, NMR and elemental analysis, and their cytotoxicities were evaluated against human chronic myeloid leukemia K562 cell lines. The cytotoxicity could be improved by the introduction of planar aromatic chromophore moiety to the parent compound, Ge-132.

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  • 收稿日期:  2007-06-29
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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