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a College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China;
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b College of Pharmacy, Kunming College of Medicine, Kunming 650031, China;
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c Pharmacy School of Wenzhou Medical College, Wenzhou 325035, China;
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d Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China
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Received Date:
05 December 2006
- Fund Project:
ritte for useful discussions.
oise Gué
This work is by part financially supported by the Yunnan Provicial Foundation of Applied Basic Research (PI:R.P.Zhang),Chine-France PRA (No.PRA BT 02-01) and EGIDE Foundation.Y.Zhao also would like to express his thankfulness to Chinese Ministry of Education and Mr.Ka-shing Li for the Cheung Kong Scholars Chair Professorship at Zhejiang University while this work was finally accomplished.We thank Dr.Franç
Abstract:
Three new diarylheptanoids, i. e., sodium(5S, 2E)-1, 7-bis(4-hydroxyphenyl)-1-hydroxy-2-hepten-5-sulfonate (1), sodium(5S, 2E)-1, 7-bis(4-hydroxyphenyl)-1-hydroxy-2-hepten-5-sulfonate (2) and 3, 5-diacetoxy-1-(3-methoxy-4, 5-dihydroxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)heptane (3) were isolated from the rhizomes of Zingiber officinale. The structures of the new compounds were elucidated on the basis of spectroscopic methods. The antioxidant activities of 3 were assayed by in vitro models involving DPPH free radicals and superoxide anion radicals.