Citation: Yue Rong Wang, Ping Hu, Qiong Lin Liang, Guo An Luo, Yi Ming Wang. Voltammetric determination of uric acid by using gold nanotubule electrode[J]. Chinese Chemical Letters, ;2007, 18(9): 1111-1114. doi: 10.1016/j.cclet.2007.07.034 shu

Voltammetric determination of uric acid by using gold nanotubule electrode

a School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China;
b Department of Chemistry, Tsinghua University, Beijing 100084, China;
c School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China

Received Date: 8 May 2007

Fund Project: This work was supported by the National Natural Science Foundation of China (No.20475031) and the "973" National Key Foundational Research Project of China (No.2001CB510305).

Gold nanotubule membranes were prepared by using electroless deposition of gold within the pores and surfaces of polycarbonate track-etched membranes. And the gold nanotubule membrane was used as an electrode for determination of uric acid in urine samples for the first time. In Britton-Robinson buffer of pH 4.56, uric acid exhibited well-defined differential pulse voltammograms. And the interference between coexistent ascorbic acid and uric acid was overcome owing to the attractive ability of the gold nanotubule electrode to yield a large anodic peak difference ca. 0.404 V (vs. SCE). The proposed method was then applied to the determination of uric acid in urine without any pretreatment.
- Gold nanotubule,
- Electrode,
- Uric acid,
- Urine
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