Citation: Ya Nan Liu, Jing Hua Xue, Na Feng, Ping Wu, Xing Zhong Liu, Xiao Yi Wei. A new cyclodipeptide from the cultures of Geotrichum candidum[J]. Chinese Chemical Letters, ;2007, 18(9): 1081-1083. doi: 10.1016/j.cclet.2007.07.003 shu

A new cyclodipeptide from the cultures of Geotrichum candidum

Ya Nan Liu ^a,c, ,
Jing Hua Xue ^a ,
Na Feng ^a ,
Ping Wu ^a ,
Xing Zhong Liu ^b ,
Xiao Yi Wei ^a

a South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China;
b Institute of Microbiology, Chinese Academy of Sciences, Beijing 10080, China;
c Graduate University of Chinese Academy of Sciences, Beijing 100049, China

Received Date: 22 March 2007

Fund Project: We thank Mr.Ruiqiang Chen,Guangzhou Institute of Chemistry,Chinese Academy of Sciences (CAS),for NMR measurements,Dr.Dongmei Fang,Chengdu Institute of Biology,CAS,for HRESIMS data,and Dr.Jianlan You,Guangzhou Institute of Biomedicine and Health,CAS,for MABA.This work was supported by an NSFC grant (No.20672114).

A new cyclodipeptide, cyclo (phenylalanyl-N-methyltyrosyl) 1, was isolated from the mycelial solid cultures of Geotrichum candidum. Its structure was elucidated by spectroscopic methods. The antifungal activity of the new compound against Peronophythora litchii was assessed by microplate Alamar blue assay (MABA).
- Cyclo (phenylalanyl-N-methyltyrosyl),
- Cyclodipeptide,
- Geotrichum,
- Geotrichum candidum,
- Peronophythora litchi,
- Antifungal activity
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