引用本文:
Ping Xue, Xiang Hui Yan, Zheng Wang. Lipase immobilized on HOOC-MCF: A highly enantioselective catalyst for transesterification resolution of (R, S)-1-phenylethanol[J]. Chinese Chemical Letters,
2007, 18(8): 929-932.
doi:
10.1016/j.cclet.2007.06.005
Citation: Ping Xue, Xiang Hui Yan, Zheng Wang. Lipase immobilized on HOOC-MCF: A highly enantioselective catalyst for transesterification resolution of (R, S)-1-phenylethanol[J]. Chinese Chemical Letters, 2007, 18(8): 929-932. doi: 10.1016/j.cclet.2007.06.005
Citation: Ping Xue, Xiang Hui Yan, Zheng Wang. Lipase immobilized on HOOC-MCF: A highly enantioselective catalyst for transesterification resolution of (R, S)-1-phenylethanol[J]. Chinese Chemical Letters, 2007, 18(8): 929-932. doi: 10.1016/j.cclet.2007.06.005
Lipase immobilized on HOOC-MCF: A highly enantioselective catalyst for transesterification resolution of (R, S)-1-phenylethanol
摘要:
Pseudomonas cepacia lipase (PSL) immobilized on the carboxyl-functionalized meso-cellular foams (HOOC-MCF) was used for the transesterification resolution of (R, S)-1-phenylethanol in organic solvent. The results showed that the ee value of (S)-1-phenylethanol and (R)-1-phenylethyl acetate reached 99% with 50% conversion of 1-phenylethanol using toluene as solvent.Furthermore, it was found that PSL/HOOC-MCF exhibited high enantioselectivity in organic solvent with log P≤2 such as toluene and hexane.
English
Lipase immobilized on HOOC-MCF: A highly enantioselective catalyst for transesterification resolution of (R, S)-1-phenylethanol
Abstract:
Pseudomonas cepacia lipase (PSL) immobilized on the carboxyl-functionalized meso-cellular foams (HOOC-MCF) was used for the transesterification resolution of (R, S)-1-phenylethanol in organic solvent. The results showed that the ee value of (S)-1-phenylethanol and (R)-1-phenylethyl acetate reached 99% with 50% conversion of 1-phenylethanol using toluene as solvent.Furthermore, it was found that PSL/HOOC-MCF exhibited high enantioselectivity in organic solvent with log P≤2 such as toluene and hexane.
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Key words:
- Immobilized lipase
- / Enantioselectivity
- / Chiral resolution
- / 1-Phenylethanol
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