A new naphthoquinoneimine derivative from the marine algal-derived endophytic fungus Aspergillus niger EN-13

Yi Zhang Xiao Ming Li Chang Yun Wang Bin Gui Wang

引用本文: Yi Zhang,  Xiao Ming Li,  Chang Yun Wang,  Bin Gui Wang. A new naphthoquinoneimine derivative from the marine algal-derived endophytic fungus Aspergillus niger EN-13[J]. Chinese Chemical Letters, 2007, 18(8): 951-953. doi: 10.1016/j.cclet.2007.05.054 shu
Citation:  Yi Zhang,  Xiao Ming Li,  Chang Yun Wang,  Bin Gui Wang. A new naphthoquinoneimine derivative from the marine algal-derived endophytic fungus Aspergillus niger EN-13[J]. Chinese Chemical Letters, 2007, 18(8): 951-953. doi: 10.1016/j.cclet.2007.05.054 shu

A new naphthoquinoneimine derivative from the marine algal-derived endophytic fungus Aspergillus niger EN-13

  • 基金项目:

    This work was partially supported by the fund of Key Laboratory of Marine Drugs (Ocean University of China), Ministry of Education[KLMD(OUC)2004] and by the National Natural Science Foundation of China (No. 30530080). A program supported by the Department of Science and Technology of Shandong Province (No. 2006GG2205023) and by the Guangdong Key Laboratory of Marine Materia Medica is also gratefully acknowledged. The authors would also like to acknowledge the anonymous referees for their valuable comments and suggestions to the manuscript.

摘要: Cultivation of an endophytic fungus Aspergillus niger EN-13 that was isolated from the inner tissue of the marine brown alga Colpomenia sinuosa resulted in the characterization of a new naphthoquinoneimine derivative, namely, 5, 7-dihydroxy-2-[1-(4-methoxy-6-oxo-6H-pyran-2-yl)-2-phenylethylamino]-[1, 4]naphthoquinone. The structure of the new compound was established on the basis of various NMR spectroscopic analyses including 2D NMR techniques, EI-MS, and HR-ESI-MS. This compound displayed moderate antifungal activity.

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  • 收稿日期:  2007-03-12
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