Citation: Jian Jiang, De Cai Wang, Wei Lin, Ping Kai Ouyang. Convenient synthesis of (4R, 5R)-4, 5-bis(aminomethyl)-2-isopropyl-1, 3-dioxolane[J]. Chinese Chemical Letters, ;2007, 18(7): 783-784. doi: 10.1016/j.cclet.2007.05.035 shu

Convenient synthesis of (4R, 5R)-4, 5-bis(aminomethyl)-2-isopropyl-1, 3-dioxolane

College of Life Science and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing 210009, China

Received Date: 26 February 2007

A convenient approach for the preparation of (4R, 5R)-4, 5-bis(aminomethyl)-2-isopropyl-l, 3-dioxolane is described. The target compound via two steps is synthesized from diethyl-2, 3-O-isobutylidene-D-tartrate, through ammonolysis and reduction.
- Heptaplatin,
- Aminomethyl,
- Intermediate,
- Anticancer drug
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