Citation: Jing Yang, Xiaofang Wang, Hui Wen, Fang Qin, Guang Zhong Yang. Design, synthesis and in vitro evaluation of phenylbenzamidine derivatives as SSRIs[J]. Chinese Chemical Letters, ;2007, 18(7): 814-816. doi: 10.1016/j.cclet.2007.05.024 shu

Design, synthesis and in vitro evaluation of phenylbenzamidine derivatives as SSRIs

Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Science, Beijing 100050, China

Received Date: 6 April 2007

Fund Project: The study was supported by the National Natural Science Foundation of China (No. 30572233) and Beijing Natural Science Foundation (No. 7062045).

A series of phenylbenzamidine analogs were synthesized and tested for their biological activities of inhibiting the reuptake of 5-HT. All of them were new compounds, and their structures were confirmed by ¹HNMR, MS and XRD.
- SSRIs,
- Phenylbenzamidine,
- XRD

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