Assembling and releasing performance of supramolecular hydrogels formed from simple drug molecule as the hydrogelator

Yu Jiang Wang Liang Yan Li Ming Tang Jian Yu

引用本文: Yu Jiang Wang,  Liang Yan,  Li Ming Tang,  Jian Yu. Assembling and releasing performance of supramolecular hydrogels formed from simple drug molecule as the hydrogelator[J]. Chinese Chemical Letters, 2007, 18(8): 1009-1012. doi: 10.1016/j.cclet.2007.05.008 shu
Citation:  Yu Jiang Wang,  Liang Yan,  Li Ming Tang,  Jian Yu. Assembling and releasing performance of supramolecular hydrogels formed from simple drug molecule as the hydrogelator[J]. Chinese Chemical Letters, 2007, 18(8): 1009-1012. doi: 10.1016/j.cclet.2007.05.008 shu

Assembling and releasing performance of supramolecular hydrogels formed from simple drug molecule as the hydrogelator

  • 基金项目:

    The financial support from the National Natural Science Foundation of China (No. 20574041) is gratefully acknowledged.

摘要: A simple drug compound, 4-oxo-4-(2-pyridinylamino) butanoic acid (defined as AP), was able to gel water at 4 wt%concentration under various conditions. In the superstructure, AP molecules assembled into fibrous aggregates driving by hydrogen bonds and π-π stacking interaction. The gels with different backbone structures released drug molecules in different speeds.

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  • 收稿日期:  2007-03-13
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