Citation: Yu Jiang Wang, Liang Yan, Li Ming Tang, Jian Yu. Assembling and releasing performance of supramolecular hydrogels formed from simple drug molecule as the hydrogelator[J]. Chinese Chemical Letters, ;2007, 18(8): 1009-1012. doi: 10.1016/j.cclet.2007.05.008 shu

Assembling and releasing performance of supramolecular hydrogels formed from simple drug molecule as the hydrogelator

Laboratory of Advanced Materials, Department of Chemical Engineering, Tsinghua University, Beijing 100084, China

Received Date: 13 March 2007

Fund Project: The financial support from the National Natural Science Foundation of China (No. 20574041) is gratefully acknowledged.

A simple drug compound, 4-oxo-4-(2-pyridinylamino) butanoic acid (defined as AP), was able to gel water at 4 wt%concentration under various conditions. In the superstructure, AP molecules assembled into fibrous aggregates driving by hydrogen bonds and π-π stacking interaction. The gels with different backbone structures released drug molecules in different speeds.
- Supramolecular hydrogel,
- Hydrogelator,
- Releasing
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