Citation:
M. Bakavoli, O. Sabzevari, M. Rahimizadeh. H-Y-zeolites induced heterocyclization: Highly efficient synthesis of substituted-quinazolin-4(3H)ones under microwave irradiation[J]. Chinese Chemical Letters,
;2007, 18(5): 533-535.
doi:
10.1016/j.cclet.2007.03.029
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A highly efficient synthesis of 2-amino-N-substituted-benzamides was performed by the condensation of isatoic anhydride with several amines in solvent-free conditions under microwave irradiation. H-Y-zeolites induced heterocyclization of these products with ortho-esters under similar conditions afforded the relevant substituted-quinazolin-4(3H) ones in high yields.
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Keywords:
- Isatoic anhydride,
- 2-Aminobenzamide,
- H-Y-zeolite,
- Quinazolinones
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