Synthesis of a new series of anti-rhinovirus compounds

Shi Yong Fan Chun Lai Mi Jun Yang Song Li Zhi Bing Zheng

引用本文: Shi Yong Fan,  Chun Lai Mi,  Jun Yang,  Song Li,  Zhi Bing Zheng. Synthesis of a new series of anti-rhinovirus compounds[J]. Chinese Chemical Letters, 2007, 18(4): 400-402. doi: 10.1016/j.cclet.2007.02.008 shu
Citation:  Shi Yong Fan,  Chun Lai Mi,  Jun Yang,  Song Li,  Zhi Bing Zheng. Synthesis of a new series of anti-rhinovirus compounds[J]. Chinese Chemical Letters, 2007, 18(4): 400-402. doi: 10.1016/j.cclet.2007.02.008 shu

Synthesis of a new series of anti-rhinovirus compounds

  • 基金项目:

    This work was supported by the National Basic Research Program of China (No. 2004CB 518908) and the National Natural Science Foundation of China (No. 30472092).

摘要: The synthesis of a series of 3,6-dichloropyridazine derivatives was described. In vitro experiment, all compounds exhibited an anti-rhinovirus activity, and one of the compounds 6g showed the comparable activity as our lead compound pirodavir.

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  • 收稿日期:  2006-11-29
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