引用本文:
Shou Wen Jin, Bin Liu, Wan Zhi Chen. Pd(OAc)2 catalyzed synthesis of heteroaryl-substituted 1,8-naphthyridine derivatives via C-N-coupling reactions of chloronaphthyridines[J]. Chinese Chemical Letters,
2007, 18(4): 383-386.
doi:
10.1016/j.cclet.2007.01.024
Citation: Shou Wen Jin, Bin Liu, Wan Zhi Chen. Pd(OAc)2 catalyzed synthesis of heteroaryl-substituted 1,8-naphthyridine derivatives via C-N-coupling reactions of chloronaphthyridines[J]. Chinese Chemical Letters, 2007, 18(4): 383-386. doi: 10.1016/j.cclet.2007.01.024
Citation: Shou Wen Jin, Bin Liu, Wan Zhi Chen. Pd(OAc)2 catalyzed synthesis of heteroaryl-substituted 1,8-naphthyridine derivatives via C-N-coupling reactions of chloronaphthyridines[J]. Chinese Chemical Letters, 2007, 18(4): 383-386. doi: 10.1016/j.cclet.2007.01.024
Pd(OAc)2 catalyzed synthesis of heteroaryl-substituted 1,8-naphthyridine derivatives via C-N-coupling reactions of chloronaphthyridines
摘要:
An efficient route to synthesize the heteroaryl-substituted 1,8-naphthyridine derivatives was described. Eight 2-heteroaryl-and 2,7-diheteroaryl-l,8-naphthyridine derivatives were obtained through palladium-catalyzed C-N-coupling reactions of chloronaphthyridines with imidazole, benzimidazole, morpholine, 3,5-dimethylpyrazole, and phthalimide in moderate to good yields.
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关键词:
- Palladium
- / Naphthyridine
- / C-N-coupling reaction
- / Catalyst
English
Pd(OAc)2 catalyzed synthesis of heteroaryl-substituted 1,8-naphthyridine derivatives via C-N-coupling reactions of chloronaphthyridines
Abstract:
An efficient route to synthesize the heteroaryl-substituted 1,8-naphthyridine derivatives was described. Eight 2-heteroaryl-and 2,7-diheteroaryl-l,8-naphthyridine derivatives were obtained through palladium-catalyzed C-N-coupling reactions of chloronaphthyridines with imidazole, benzimidazole, morpholine, 3,5-dimethylpyrazole, and phthalimide in moderate to good yields.
-
Key words:
- Palladium
- / Naphthyridine
- / C-N-coupling reaction
- / Catalyst
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