Citation: Hua Han, Yang Hua Yi, Ling Li, Xiao Hua Wang, Bao Shu Liu, Peng Sun, Min Xiang pan. A new triterpene glycoside from sea cucumber Holothuria leucospilota[J]. Chinese Chemical Letters, ;2007, 18(2): 161-164. doi: 10.1016/j.cclet.2006.12.027 shu

A new triterpene glycoside from sea cucumber Holothuria leucospilota

Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University, Shanghai 200433, China

Received Date: 30 August 2006

Fund Project: This research was supported by the State Foundation for High-tech Project "863" from the Ministory of Science and Technology,China (No. 2001AA624100).We thank Professor Yu Lin Liao for taxonomic identification of the sea cucumber.

A new triterpene glycoside, leucospilotaside A, along with a known saponin, isolated from sea cucumber Holothuria leucospilota, and its structure was elucidated as 3β-O-[4-O-sodiumsulfate-β-D-quinovopyranosyl-(1→2)-β-D-xylopyranosyl]-holosta-22-ketone-9-en-17α,25α-diol (1) by extensive spectroscopic analysis and chemical methods. Leucospilotaside A (1) has a ketone carbonyl group (22) in the aglycon side chain.
- Sea cucumber,
- Holothuria leucospilota,
- Triterpene glycoside,
- Leucospilotaside A
1. [1]
  Zheng-Biao Zou , Tai-Zong Wu , Chun-Lan Xie , Yuan Wang , Yan Li , Gang Zhang , Rong Chao , Lian-Zhong Luo , Li-Sheng Li , Xian-Wen Yang . neo-Dicitrinols A–C: Unprecedented PKS-NRPS hybrid citrinin dimers with ferroptosis inhibitory activity from the deep-sea-derived Penicillium citrinum W22. Chinese Chemical Letters, 2024, 35(12): 109723-. doi: 10.1016/j.cclet.2024.109723

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