Citation: Mohsen Keyvanfard, Khadijeh Alizad. Determination of isoproterenol in pharmaceutical and biological samples using a pyrogallol red multiwalled carbon nanotube paste electrode as a sensor[J]. Chinese Journal of Catalysis, ;2016, 37(4): 579-583. doi: 10.1016/S1872-2067(15)61036-1 shu

Determination of isoproterenol in pharmaceutical and biological samples using a pyrogallol red multiwalled carbon nanotube paste electrode as a sensor

Mohsen Keyvanfard ^, ,
Khadijeh Alizad

1.
Department of Chemistry, Majlesi Branch, Islamic Azad University, Isfahan, Iran

Corresponding author: Mohsen Keyvanfard,
Received Date: 10 October 2015
Available Online: 5 January 2016

Isoproterenol (ISPR) is an important catecholamine-based drug that is widely used in the treatment of heart disease. However, overdose of this drug is very dangerous to the human body. In this study, a new sensor based on a pyrogallol red modified-multiwalled carbon nanotube paste electrode (PGRMMWCNTPE) was prepared and used for high sensitivity determination of ISPR in aqueous solution. Electrocatalytic oxidation of ISPR at the PGRMMWCNTPE was investigated by chronoamperometry, cyclic voltammetry, and square-wave voltammetry. The values of the catalytic rate constant, electron transfer coefficient, and diffusion coefficient for ISPR oxidation were then calculated using voltammetric data. A linear calibration curve was constructed for ISPR concentration in the range 0.8-570 μmol/L with a detection limit of 0.47 μmol/L ISPR. The sensor was then applied to the determination of ISPR in urine and drug samples with satisfactory results.
- Isoproterenol,
- Pharmaceutical analysis,
- Pyrogallol red,
- Voltammetry,
- Multiwalled carbon nanotubes
1. [1]
  [1] L. Goodman, A. Gilman, The Pharmacological Basis of Therapeutics, 9 ed., McGraw-Hill Professional, New York, 1996, 105.
2. [2]
  [2] L. Elrod, J. L. Schmit, J. A. Morley, J. Chromatogr. A, 1996, 723, 235-241.
3. [3]
  [3] B. J. Sanghavi, S. M. Mobin, P. Mathur, G. K. Lahiri, A. K. Srivastava, Biosens. Bioelectron., 2013, 39, 124-132
4. [4]
  [4] A. A. Ensafi, H. K. Maleh, Int. J. Electrochem. Sci., 2010, 5, 1484-1495.
5. [5]
  [5] H. Karimi-Maleh, F. Tahernejad-Javazmi, A. A. Ensafi, R. Moradi, S. Mallakpour, H. Beitollahi, Biosens. Bioelect., 2014, 60, 1-7.
6. [6]
  [6] M. Keyvanfard, H. Karimi-Maleh, K. Alizad, Chin. J. Catal., 2013, 34, 1883-1889.
7. [7]
  [7] M. Keyvanfard, M. Ahmadi, F. Karimi, K. Alizad, Chin. Chem. Lett., 2014, 25, 1244-1246.
8. [8]
  [8] A. S. Isfahani, M. Keyvanfard, B. Rezaei, K. Alizad, Current Nanosci., 2014, 10, 512-520.
9. [9]
  [9] J. Barek, J. Fischer, J. C. Moreira, J. Wang, in: K. Kalcher, R. Metelka, I. Švancara, K. Vytřas eds., Sensing in Electroanalysis, University Press Centre, Pardubice, 2013/2014, Volume 8.
10. [10]
  [10] A. A. Ensafi, E. Khoddami, H. Karimi-Maleh, Int. J. Electrochem. Sci., 2011, 6, 2596-2608.
11. [11]
  [11] B. J. Sanghavi, W. Varhue, J. L. Chávez, C. F. Chou, N. S. Swami, Anal. Chem., 2014, 86, 4120-4125.
12. [12]
  [12] S. N. Azizi, S. Ghasemi, N. S. Gilani, Chin. J. Catal., 2014, 35, 383-390.
13. [13]
  [13] A. A. Ensafi, M. Lotfi, H. Karimi-Maleh, Chin. J. Catal., 2012, 33, 487-493.
14. [14]
  [14] B. Habibi, M. Abazari, M. H. Pournaghi-Azar, Chin. J. Catal., 2012, 33, 1783-1790.
15. [15]
  [15] H. Karimi-Maleh, F. Tahernejad-Javazmi, N. Atar, M. L. Yola, V. K. Gupta, A. A. Ensafi, Ind. Eng. Chem. Res., 2015, 54, 3634-3639.
16. [16]
  [16] M. R. Ganjali, P. Norouzi, M. Ghorbani, A. Sepehri, Talanta, 2005, 66, 1225-1233.
17. [17]
  [17] P. Norouzi, M. R. Ganjali, M. Zare, A. Mohammadi, J. Pharm. Sci., 2007, 96, 2009-2017.
18. [18]
  [18] P. Norouzi, M. R. Ganjali, T. Alizadeh, P. Daneshgar, Electroanalysis, 2006, 18, 947-954.
19. [19]
  [19] P. Norouzi, M. R. Ganjali, L. Hajiaghababaei, Anal. Lett., 2006, 39, 1941-1953.
20. [20]
  [20] T. Alizadeh, M. R. Ganjali, M. Zare, P. Norouzi, Electrochim. Acta, 2010, 55, 1568-1574.
21. [21]
  [21] B. J. Sanghavi, A. K. Srivastava, Electrochim. Acta, 2010, 55, 8638-8648.
22. [22]
  [22] M. L. Yola, N. Atar, Electrochim. Acta, 2014, 119, 24-31.
23. [23]
  [23] B. J. Sanghavi, A. K. Srivastava, Electrochim. Acta, 2011, 56, 4188-4196.
24. [24]
  [24] B. J. Sanghavi, P. K. Kalambate, S. P. Karna, A. K. Srivastava, Talanta, 2014, 120, 1-9
25. [25]
  [25] M. L. Yola, N. Atar, Z. Üstündağ, A. O. Solak, J. Electroanal. Chem., 2013, 698, 9-16.
26. [26]
  [26] M. L. Yola, T. Eren, N. Atar, Sens. Actuators B, 2014, 195, 28-35.
27. [27]
  [27] H. Karimi-Maleh, P. Biparva, M. Hatami, Biosens. Bioelect., 2013, 48, 270-275.
28. [28]
  [28] R. Sadeghi, H. Karimi-Maleh, A. Bahari, M. Taghavi, Phys. Chem. Liq., 2013, 51, 704-714.
29. [29]
  [29] R. Moradi, S. A. Sebt, H. Karimi-Maleh, R. Sadeghi, F. Karimi, A. Bahari, H. Arabi, Phys. Chem. Chem. Phys., 2013, 15, 5888-5897.
30. [30]
  [30] M. Najafi, M. A. Khalilzadeh, H. Karimi-Maleh, Food Chem., 2014, 158, 125-131.
31. [31]
  [31] M. Keyvanfard, V. Khosravi, H. Karimi-Maleh, K. Alizad, B. Rezaei, J. Mol. Liq., 2013, 177, 182-189.
32. [32]
  [32] M. Elysi, M. A. Khalilzadeh, H. Karimi-Maleh, Food Chem., 2013, 141, 4311-4317.
33. [33]
  [33] M. Keyvanfard, R. Salmani-Mobarakeh, H. Karimi-Maleh, K. Alizad, Chin. J. Catal., 2014, 35, 1166-1172.
34. [34]
  [34] A. A. Ensafi, H. Karimi-Maleh, J. Electroanal. Chem., 2010, 640, 75-83
35. [35]
  [35] E. M. Silva, R. M. Takeuchi, A. L. Santos, Food Chem., 2015, 173, 763-769.
36. [36]
  [36] H. Karimi-Maleh, S. Rostami, V. K. Gupta, M. Fouladgar, J. Mol. Liq., 2015, 201, 102-107.
1. [1]
  Zhenlin Zhou , Siyuan Chen , Yi Liu , Chengguo Hu , Faqiong Zhao . A New Program of Voltammetry Experiment Teaching Based on Laser-Scribed Graphene Electrode. University Chemistry, 2024, 39(2): 358-370. doi: 10.3866/PKU.DXHX202308049
2. [2]
  Xiufang Wang , Donglin Zhao , Kehua Zhang , Xiaojie Song . “Preparation of Carbon Nanotube/SnS₂ Photoanode Materials”: A Comprehensive University Chemistry Experiment. University Chemistry, 2024, 39(4): 157-162. doi: 10.3866/PKU.DXHX202308025
3. [3]
  Han WANG , Baihui CHEN , Chunlai WANG , Zhitao SHAO . Preparation and performance of lithium-sulfur battery of Ni₂P/carbon nanotube modified separator. Chinese Journal of Inorganic Chemistry, 2026, 42(5): 933-943. doi: 10.11862/CJIC.20250334
4. [4]
  Cun WANG , Shaohan XU , Yuqian ZHANG , Yaoyao ZHANG , Tao GONG , Rong WEN , Yuhang LIAO , Yanrong REN . Terbium complex electrochemiluminescent emitters: Synthesis and application in the detection of epinephrine. Chinese Journal of Inorganic Chemistry, 2025, 41(7): 1351-1360. doi: 10.11862/CJIC.20240427
5. [5]
  Mengyun Wu , Yuxin Deng , Wenhui Wang , Dongdong Xu , Langui Xie , Peipei Sun . 电化学合成4-氯-2-三异丙基硅基喹啉. University Chemistry, 2026, 41(5): 222-229. doi: 10.12461/PKU.DXHX202511044
6. [6]
  Ying Yang , Yonghan Wu , Zixuan Li , Lu Zhang , Rongqin Lin , Yefan Zhang , Jiquan Liu , Xiaohui Ning , Yan Li , Bin Cui . Visualization Simulation Experiment of Cyclic Voltammetry (CV) Based on Python. University Chemistry, 2025, 40(10): 233-242. doi: 10.12461/PKU.DXHX202412024
7. [7]
  Hailang JIA , Hongcheng LI , Pengcheng JI , Yang TENG , Mingyun GUAN . Preparation and performance of N-doped carbon nanotubes composite Co₃O₄ as oxygen reduction reaction electrocatalysts. Chinese Journal of Inorganic Chemistry, 2024, 40(4): 693-700. doi: 10.11862/CJIC.20230402
8. [8]
  Shuhong Xiang , Lv Yang , Yingsheng Xu , Guoxin Cao , Hongjian Zhou . Selective electrosorption of Cs(Ⅰ) from high-salinity radioactive wastewater using CNT-interspersed potassium zinc ferrocyanide electrodes. Acta Physico-Chimica Sinica, 2025, 41(9): 100097-0. doi: 10.1016/j.actphy.2025.100097
9. [9]
  Chen Pu , Daijie Deng , Henan Li , Li Xu . Fe_0.64Ni_0.36@Fe₃NiN Core-Shell Nanostructure Encapsulated in N-Doped Carbon Nanotubes for Rechargeable Zinc-Air Batteries with Ultralong Cycle Stability. Acta Physico-Chimica Sinica, 2024, 40(2): 2304021-0. doi: 10.3866/PKU.WHXB202304021
10. [10]
  Liqiang Huang , Peng Lin . 数-图分析法解释仪器分析实验课程教学中的难点. University Chemistry, 2025, 40(6): 353-359. doi: 10.12461/PKU.DXHX202407074
11. [11]
  Chenxu Gong , Weizhen Wang , Ruiying Zhang , Wenfeng Wang , Yuanming Li , Yaofeng Yuan , Keyin Ye . Computational Chemistry-Assisted Organic Structure Analysis (CCAOSA): A Case Study of Propeller-Shaped Hexabenzotriphenylene. University Chemistry, 2026, 41(4): 438-446. doi: 10.12461/PKU.DXHX202503076
12. [12]
  Mi Wen , Baoshuo Jia , Yongqi Chai , Tong Wang , Jianbo Liu , Hailong Wu . Improvement of Fluorescence Quantitative Analysis Experiment: Simultaneous Determination of Rhodamine 6G and Rhodamine 123 in Food Using Chemometrics-Assisted Three-Dimensional Fluorescence Method. University Chemistry, 2025, 40(4): 390-398. doi: 10.12461/PKU.DXHX202405147
13. [13]
  Haihua Yang , Minjie Zhou , Binhong He , Wenyuan Xu , Bing Chen , Enxiang Liang . Synthesis and Electrocatalytic Performance of Iron Phosphide@Carbon Nanotubes as Cathode Material for Zinc-Air Battery: a Comprehensive Undergraduate Chemical Experiment. University Chemistry, 2024, 39(10): 426-432. doi: 10.12461/PKU.DXHX202405100
14. [14]
  Xinyue Zhao , Min Wang . Teaching Differentiation of t-Test for Grouped Data in Analytical Chemistry: A Case Study of Chloride Concentration in Surface vs. Bottom Lake Water. University Chemistry, 2026, 41(3): 227-232. doi: 10.12461/PKU.DXHX202511022
15. [15]
  Liwei Wang , Guangran Ma , Li Wang , Fugang Xu . A Comprehensive Analytical Chemistry Experiment: Colorimetric Detection of Vitamin C Using Nanozyme and Smartphone. University Chemistry, 2024, 39(8): 255-262. doi: 10.3866/PKU.DXHX202312094
16. [16]
  Xiuya Ma , Yu Chen , Yan Zhang . Stories about Pharmaceuticals. University Chemistry, 2025, 40(7): 232-240. doi: 10.12461/PKU.DXHX202408003
17. [17]
  Liyang ZHANG , Dongdong YANG , Ning LI , Yuanyu YANG , Qi MA . Crystal structures, luminescent properties and Hirshfeld surface analyses of three cadmium(Ⅱ) complexes based on 2-(3-(pyridin-2-yl)-1H-pyrazol-1-yl)benzoate. Chinese Journal of Inorganic Chemistry, 2024, 40(10): 1943-1952. doi: 10.11862/CJIC.20240079
18. [18]
  Tengyue ZHANG , Jingjing FENG , Zili LIANG , Jia′nan DAI , Jing MA . Optimization of C-doped BiVO₄ performance for tetracycline degradation using response surface methodology-assisted orthogonal experiments. Chinese Journal of Inorganic Chemistry, 2025, 41(12): 2561-2574. doi: 10.11862/CJIC.20250104
19. [19]
  Lihua Jin , Lei Tian , Chaozhan Wang , Jiawei Liu , Quan Bai , Yan Li . Teaching Exploration and Practice of the Instrumental Analysis Experiment “Distinguishing Green Plastic Bags by Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy”. University Chemistry, 2026, 41(2): 360-365. doi: 10.12461/PKU.DXHX202502089
20. [20]
  Ziheng Zhuang , Xiao Xu , Kin Shing Chan . Superdrugs for Superbugs. University Chemistry, 2024, 39(9): 128-133. doi: 10.3866/PKU.DXHX202309040

Get Citation

PDF

XML

Metrics

PDF Downloads(0)
Abstract views(817)
HTML views(38)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142