Citation: Sajjad Salahi, Malek Taher Maghsoodlou, Nourallah Hazeri, Mojtaba Lashkari, Santiago Garcia-Granda, Laura Torre-Fernandez. An efficient green synthesis of dispirohydroquinolines via a diastereoselective one-pot eight-component reaction[J]. Chinese Journal of Catalysis, ;2015, 36(7): 1023-1028. doi: 10.1016/S1872-2067(15)60846-4 shu

An efficient green synthesis of dispirohydroquinolines via a diastereoselective one-pot eight-component reaction

1.
a Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P. O. Box 98135-674 Zahedan, Iran;

Corresponding author: Malek Taher Maghsoodlou,
Received Date: 25 January 2015
Available Online: 19 March 2015

The one-pot eight-component reaction between Meldrum's acid, an aromatic aldehyde, and an aryl amine was achieved in the presence of citric acid catalyst. The corresponding dispirohydroquinolines were obtained in good yields with excellent diastereoselectivity. This method is a combination of the Knoevenagel and Michael reactions.
- Eight-component reaction,
- Dispirohydroquinoline,
- Meldrum's acid,
- Citric acid
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沈阳化工大学材料科学与工程学院沈阳 110142