Citation: Xingquan Xiong, Chao Yi, Qian Han, Lin Shi, Sizhong Li. I₂/ionic liquid as a highly efficient catalyst for per-O-acetylation of sugar under microwave irradiation[J]. Chinese Journal of Catalysis, ;2015, 36(2): 237-243. doi: 10.1016/S1872-2067(14)60219-9 shu

I₂/ionic liquid as a highly efficient catalyst for per-O-acetylation of sugar under microwave irradiation

1.
College of Materials Science and Engineering, Huaqiao University, Xiamen 361021, Fujian, China

Corresponding author: Xingquan Xiong,
Received Date: 19 June 2014
Available Online: 29 August 2014
Fund Project: 国家自然科学基金(21004024) (21004024) 福建省自然科学基金(2011J01046) (2011J01046) 福建省“高校新世纪优秀人才支持计划”(2012FJ- NCET-ZR03) (2012FJ- NCET-ZR03) 福建省“高校杰出青年科研人才培育计划”(11FJPY02) (11FJPY02) 华侨大学中青年教师科研提升资助计划(ZQN-YX103) (ZQN-YX103) 福建省青年人才创新项目(2011J05131). (2011J05131)

A practical and highly efficient approach was developed to synthesize peracetylated sugar derivatives using a recyclable iodine/PEG₄₀₀-based ionic liquid catalyst (I₂/IL). The peracetylated sugars were readily obtained in a few minutes in excellent yields (90%-99%, 13 examples) on a multi-gram scale (50.0 mmol) by the reaction of sugar and acetic anhydride under microwave irradiation in the absence of a volatile organic solvent. The desired product was easily obtained by simple extraction with toluene from the reaction mixture, and I₂/ILs can be readily recovered and reused at least six times without obvious loss in the yield. When the scale of the per-O-acetylation reaction was increased to 50.0 mmol, the desired product was still obtained in 90% yield after five recycles.
- Peracetylated sugar,
- Iodine,
- Ionic liquid,
- Microwave irradiation
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沈阳化工大学材料科学与工程学院沈阳 110142

I2/ionic liquid as a highly efficient catalyst for per-O-acetylation of sugar under microwave irradiation

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通讯作者: 陈斌, bchen63@163.com

I₂/ionic liquid as a highly efficient catalyst for per-O-acetylation of sugar under microwave irradiation