Synthesis and bioactivity of novel pyrazole oxime derivatives containing oxazole ring

注册 English

Synthesis and bioactivity of novel pyrazole oxime derivatives containing oxazole ring

Sen-Lin Wang , Yu-Jun Shi , Hai-Bing He , Yu Li , Yang Li , Hong Dai

Citation: Sen-Lin Wang, Yu-Jun Shi, Hai-Bing He, Yu Li, Yang Li, Hong Dai. Synthesis and bioactivity of novel pyrazole oxime derivatives containing oxazole ring[J]. Chinese Chemical Letters, 2015, 26(6): 672-674. doi: 10.1016/j.cclet.2015.04.017 shu

shu

Synthesis and bioactivity of novel pyrazole oxime derivatives containing oxazole ring

Sen-Lin Wang ^a, ,
Yu-Jun Shi ^{a,b,
,} ,
Hai-Bing He ^b, ,
Yu Li ^b, ,
Yang Li ^a, ,
Hong Dai ^{b,
,}

通讯作者: Yu-Jun Shi,
Hong Dai,

基金项目:
This study was funded by the National Natural Science Foundation of China (No. 21202089) (No. 21202089)

the Research Foundation of the Six People Peak of Jiangsu Province (Nos. 2011-SWYY-009, 2013-SWYY-013) (Nos. 2011-SWYY-009, 2013-SWYY-013)

the Technology Project Fund of Nantong City (Nos. AS2013004, CP12013002). (Nos. AS2013004, CP12013002)

摘要: A series of novel pyrazole oxime derivatives containing oxazole ring were designed and synthesized. The title compounds were structurally confirmed by ¹H NMR, ¹³C NMR spectra and elemental analyses. Preliminary bioassay results showed that some of the title compounds displayed promising fungicidal activity besides insecticidal and acaricidal activity. Particularly, compound 8c exhibited potent fungicidal activity against cucumber Pseudoperonospora cubensis beyond good insecticidal activity against Aphis craccivora and Nilaparvata lugens.

关键词:

English

Synthesis and bioactivity of novel pyrazole oxime derivatives containing oxazole ring

Sen-Lin Wang ^a, ,
Yu-Jun Shi ^{a,b,
,} ,
Hai-Bing He ^b, ,
Yu Li ^b, ,
Yang Li ^a, ,
Hong Dai ^{b,
,}

1.
a School of Environmental and Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang 212003, China;
2.
b College of Chemistry and Chemical Engineering, Nantong University, Nantong 226019, China

Corresponding author: Yu-Jun Shi, Hong Dai,

Received Date: 27 February 2015
Available Online: 23 April 2015
Fund Project:

Abstract: A series of novel pyrazole oxime derivatives containing oxazole ring were designed and synthesized. The title compounds were structurally confirmed by ¹H NMR, ¹³C NMR spectra and elemental analyses. Preliminary bioassay results showed that some of the title compounds displayed promising fungicidal activity besides insecticidal and acaricidal activity. Particularly, compound 8c exhibited potent fungicidal activity against cucumber Pseudoperonospora cubensis beyond good insecticidal activity against Aphis craccivora and Nilaparvata lugens.

Key words:

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