Un-catalyzed tandem Knoevenagel-Michael reaction for the synthesis of 4,4'-(arylmethylene)bis(1H-pyrazol-5-ols) in aqueous medium

Nilesh P. Tale ,  Girdharilal B. Tiwari ,  Nandkishor N. Karade

引用本文: Nilesh P. Tale,  Girdharilal B. Tiwari,  Nandkishor N. Karade. Un-catalyzed tandem Knoevenagel-Michael reaction for the synthesis of 4,4'-(arylmethylene)bis(1H-pyrazol-5-ols) in aqueous medium[J]. Chinese Chemical Letters, 2011, 22(12): 1415-1418. doi: 10.1016/j.cclet.2011.09.004 shu
Citation:  Nilesh P. Tale,  Girdharilal B. Tiwari,  Nandkishor N. Karade. Un-catalyzed tandem Knoevenagel-Michael reaction for the synthesis of 4,4'-(arylmethylene)bis(1H-pyrazol-5-ols) in aqueous medium[J]. Chinese Chemical Letters, 2011, 22(12): 1415-1418. doi: 10.1016/j.cclet.2011.09.004 shu

Un-catalyzed tandem Knoevenagel-Michael reaction for the synthesis of 4,4'-(arylmethylene)bis(1H-pyrazol-5-ols) in aqueous medium

  • 基金项目:

    The authors are thankful to the University Grants Commission, New Delhi, India (No.MRP 32-245/2006 SR) for the financial support.

摘要: An environmentally benign un-catalyzed one-pot synthesis of 4, 4'-(arylmethylene)bis (1H-pyrazol-5-ols) has been reported via tandem Knoevenagel-Michael reaction of aldehydes with two equivalents of 3-methyl-1-phenyl-1H-pyrazol-5 (4H)-one in aqueous medium.

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  • 收稿日期:  2011-05-03
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