Response surface methodology to optimize gradient ion chromatographic separation of inorganic anions and organic acids in tobacco leaves

Rui Qi Wang ,  Na Ni Wang ,  Jia Jie Zhang ,  Yan Zhu

引用本文: Rui Qi Wang,  Na Ni Wang,  Jia Jie Zhang,  Yan Zhu. Response surface methodology to optimize gradient ion chromatographic separation of inorganic anions and organic acids in tobacco leaves[J]. Chinese Chemical Letters, 2011, 22(12): 1465-1468. doi: 10.1016/j.cclet.2011.06.011 shu
Citation:  Rui Qi Wang,  Na Ni Wang,  Jia Jie Zhang,  Yan Zhu. Response surface methodology to optimize gradient ion chromatographic separation of inorganic anions and organic acids in tobacco leaves[J]. Chinese Chemical Letters, 2011, 22(12): 1465-1468. doi: 10.1016/j.cclet.2011.06.011 shu

Response surface methodology to optimize gradient ion chromatographic separation of inorganic anions and organic acids in tobacco leaves

  • 基金项目:

    This research was financially supported by National Natural Science Foundation of China (nos.20775070, J0830413), Zhejiang Provincial Natural Science Foundation of China (no.R4080124).

摘要: The separation optimization of nine organic and inorganic anions in tobacco leaves using gradient ion chromatography by response surface methodology was investigated. In order to achieve this goal the usefulness of the chromatographic response function (CRF) for the evaluation of the two different chromatographic performance goals (resolution and analysis time) was tested. The experiments were performed according to a Box-Behnken design response surface experimental design.

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  • 收稿日期:  2011-04-06
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