Probing cytotoxicity of CdSe and CdSe/CdS quantum dots

引用本文: Yan Jie Bao, Jun Jun Li, Yi Ting Wang Lei Yu, Lei Lou, Wei Ji Du, Zi Qiang Zhu, Hui Peng, Jian Zhong Zhu. Probing cytotoxicity of CdSe and CdSe/CdS quantum dots[J]. Chinese Chemical Letters, 2011, 22(7): 843-846. doi: 10.1016/j.cclet.2010.12.008 shu

Citation: Yan Jie Bao, Jun Jun Li, Yi Ting Wang Lei Yu, Lei Lou, Wei Ji Du, Zi Qiang Zhu, Hui Peng, Jian Zhong Zhu. Probing cytotoxicity of CdSe and CdSe/CdS quantum dots[J]. Chinese Chemical Letters, 2011, 22(7): 843-846. doi: 10.1016/j.cclet.2010.12.008 shu

Probing cytotoxicity of CdSe and CdSe/CdS quantum dots

Institutes for Advanced Interdisciplinary Research, East China Normal University, Shanghai 200062, China
基金项目:
The project is supported by National Natural Science Foundation of China (No.60976004) and Shanghai Municipal Commission for Science and Technology (No.09JC1405300).

摘要: Toxicities of CdSe and CdSe/CdS quantum dots (QDs) synthesized by ultrasound-assisted methods were investigated in vitro and in vivo. Five human cell lines were used to assess the cytotoxicity of as-prepared CdSe and CdSe/CdS by assays of MTT viability, red blood cell hemolysis, flow cytometry, and fluorescence imaging. The results show that these QDs may be cytotoxic by their influence in S and G2 phases in cell cycles. The cytotoxicity of QDs depends on both the physicochemical properties and related to target cells.

关键词:

Cytotoxicity
/ Quantum dots
/ CdSe
/ CdSe/CdS
/ Cell

English

Probing cytotoxicity of CdSe and CdSe/CdS quantum dots

Institutes for Advanced Interdisciplinary Research, East China Normal University, Shanghai 200062, China
Received Date: 09 October 2010
Fund Project:
The project is supported by National Natural Science Foundation of China (No.60976004) and Shanghai Municipal Commission for Science and Technology (No.09JC1405300).

Abstract: Toxicities of CdSe and CdSe/CdS quantum dots (QDs) synthesized by ultrasound-assisted methods were investigated in vitro and in vivo. Five human cell lines were used to assess the cytotoxicity of as-prepared CdSe and CdSe/CdS by assays of MTT viability, red blood cell hemolysis, flow cytometry, and fluorescence imaging. The results show that these QDs may be cytotoxic by their influence in S and G2 phases in cell cycles. The cytotoxicity of QDs depends on both the physicochemical properties and related to target cells.

Key words:

Cytotoxicity
/ Quantum dots
/ CdSe
/ CdSe/CdS
/ Cell

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Probing cytotoxicity of CdSe and CdSe/CdS quantum dots

English

Probing cytotoxicity of CdSe and CdSe/CdS quantum dots

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

Probing cytotoxicity of CdSe and CdSe/CdS quantum dots

English

Probing cytotoxicity of CdSe and CdSe/CdS quantum dots

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

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