引用本文:
Cheng Quan Wang, Hui Wang, Yan Ming Liu. Capillary electrophoresis with direct chemiluminescence detection for the analysis of catecholamines in human urine[J]. Chinese Chemical Letters,
2007, 18(4): 452-454.
doi:
10.1016/j.cclet.2007.02.009
Citation: Cheng Quan Wang, Hui Wang, Yan Ming Liu. Capillary electrophoresis with direct chemiluminescence detection for the analysis of catecholamines in human urine[J]. Chinese Chemical Letters, 2007, 18(4): 452-454. doi: 10.1016/j.cclet.2007.02.009
Citation: Cheng Quan Wang, Hui Wang, Yan Ming Liu. Capillary electrophoresis with direct chemiluminescence detection for the analysis of catecholamines in human urine[J]. Chinese Chemical Letters, 2007, 18(4): 452-454. doi: 10.1016/j.cclet.2007.02.009
Capillary electrophoresis with direct chemiluminescence detection for the analysis of catecholamines in human urine
摘要:
A rapid and sensitive method for the analysis of three catecholamines by capillary electrophoresis (CE) with direct chemiluminescence (CL) detection is described. The detection limits (S/N=3) were 1.3×10-8 g/mL for isoprenaline,1.0×10-8 g/mL for epinephrine and 2.8×10-8 g/mL for dopamine. The proposed method was successfully applied to the analysis of catecholamines in urine samples of cigarette smokers and nonsmokers. The results showed that there is a close relation between the release of dopamine in human body fluids and cigarette smoking/nonsmoking.
English
Capillary electrophoresis with direct chemiluminescence detection for the analysis of catecholamines in human urine
Abstract:
A rapid and sensitive method for the analysis of three catecholamines by capillary electrophoresis (CE) with direct chemiluminescence (CL) detection is described. The detection limits (S/N=3) were 1.3×10-8 g/mL for isoprenaline,1.0×10-8 g/mL for epinephrine and 2.8×10-8 g/mL for dopamine. The proposed method was successfully applied to the analysis of catecholamines in urine samples of cigarette smokers and nonsmokers. The results showed that there is a close relation between the release of dopamine in human body fluids and cigarette smoking/nonsmoking.
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Key words:
- Capillary electrophoresis
- / Catecholamines
- / Chemiluminescence detection
- / Urine
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