Citation: Bing ZHENG, Jin Long WU, Shao Jun XU, Jian Feng SHI, Yao Zu CHEN. A Facile and Highly Stereoselective Reductive Debromination of Anhydro-6-(R)-Hydroxyethyl-6-Bromopenicillin[J]. Chinese Chemical Letters, ;2000, 11(5): 385-386. shu

A Facile and Highly Stereoselective Reductive Debromination of Anhydro-6-(R)-Hydroxyethyl-6-Bromopenicillin

a Department of Chemistry, Zhejiang University, Hangzhou 310027;
b National Laboratory of Applied Organic Chemistry, Lanzhou 730000

Received Date: 16 October 1999
Revised Date: 6 January 2000

Reductive debromination of anhydro-6-(R)-hydroxyethyl-6-bromopenicillin 7 by zinc in ammonium acetate gave 9 in 81% yield with high stereoselectivity of 6-(α):6-(β)=13:1.
- Reductive debromination,
- stereoselectivity,
- anhydro-6-(R)-hydroxyethyl-6-bromo-penicillin
1. [1]
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2. [2]
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3. [3]
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4. [4]
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5. [5]
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6. [6]
  . . University Chemistry, 2024, 39(6): 0-0.
7. [7]
  . 第41卷第6期封面和目次. Acta Physico-Chimica Sinica, 2025, 41(6): -.
8. [8]
  Pan Liu , Yanming Sun , Alberto J. Fernández-Carrión , Bowen Zhang , Hui Fu , Lunhua He , Xing Ming , Congling Yin , Xiaojun Kuang . Bismuth-based halide double perovskite Cs₂KBiCl₆: Disorder and luminescence. Chinese Chemical Letters, 2024, 35(5): 108641-. doi: 10.1016/j.cclet.2023.108641
9. [9]
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11. [11]
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12. [12]
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14. [14]
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15. [15]
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16. [16]
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17. [17]
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19. [19]
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