Citation: Chen Pusen, Chen Haiming, Zhang Guanfei, Chen Weijun, Chen Wenxue. Synthesis, Characterization and Interaction of Syringic Acid-Copper Complex with DNA[J]. Chemistry, ;2018, 81(2): 170-174. shu

Synthesis, Characterization and Interaction of Syringic Acid-Copper Complex with DNA

Hainan University, Haikou 570228

Corresponding author: Chen Haiming, hmchen168@126.com
Received Date: 28 July 2017
Accepted Date: 20 November 2017

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Since platinum complexes have been found to have anti-cancer effects, the research of small molecule and metal ion coordination has become an important way to discover anti-cancer drugs. In this paper, the complex of syringic acid and copper ion was studied by UV, IR and MS, and its composition is confirmed to be (C₉H₈O₅)Cu·H₂O. Then, the effects of syringic acid-copper complex and DNA were studied by UV spectroscopy, fluorescence spectroscopy, and viscosity measurement. It was proved that the combination of syringic acid-copper complex and DNA is the insertion mode.
- yringic acid,
- Copper metal complex,
- ct-DNA,
- Structural characterization,
- Mode of action
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