Citation: Jia Xing HUANG, Xiao Mei LIANG, Dao Quan WANG. A New Synthetic Route to 12-Oxo-1, 15-pentadecanlactam[J]. Chinese Chemical Letters, ;2004, 15(2): 169-170. shu

A New Synthetic Route to 12-Oxo-1, 15-pentadecanlactam

Key Laboratory of Pesticide Chemistry and Application Technology, Department of Applied Chemistry, China Agricultural University, Beijing 100094

Received Date: 11 February 2003

12-Oxo-1, 15-pentadecanlactam 7 was synthesized from cyclododecanone with a total yield of 36% in a seven-step reaction. The azide 5 to 12-nitro-1, 15-pentadecanlactam 6 is the key step featured by direct ring expansion.
- Macrolactam,
- synthesis,
- ring enlargement
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