Citation: Jiang Pengfei, Yang Hongcheng, Ji Chenyang, Chen Zhu, Nie Libo. Progress in Quartz Crystal Microbalance and Its Application in Biological Detection[J]. Chemistry, ;2018, 81(2): 129-133. shu

Progress in Quartz Crystal Microbalance and Its Application in Biological Detection

College of Life Science and Chemistry, Hunan University of Technology, Zhuzhou 412007

Corresponding author: Nie Libo, libonie@aliyun.com
Received Date: 20 August 2017
Accepted Date: 31 October 2017

Figures(3)

Quartz crystal microbalance (QCM) is a significant analytical tool which has the advantages of high sensitivity, label-free and real-time detection. In the field of biological detection, QCM combining with signal amplification methods is widely used in ultrasensitive detection of biomolecules. The novel QCM with dissipation (QCM-D) is mainly used to investigate the microscopic processes such as adsorption/desorption and configuration change of biomolecules by studying the thickness and viscoelasticity of the thin film. This paper reviewed the construction of QCM and QCM-D biosensors as well as their research progress in the detection of DNA, protein, cell and microorganism.
- Quartz crystal microbalance,
- Biological detection,
- Biosensor
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沈阳化工大学材料科学与工程学院沈阳 110142