Citation: Su Changhui, Liu Xia, Pan Tao, Shen Hong, Hang Zhaoqin. One-Pot Synthesis of 1, 4-Disubstituted 1, 2, 3-Triazoles from 1, 1-Dibromoalkenes[J]. Chemistry, ;2019, 82(12): 1130-1133. shu

One-Pot Synthesis of 1, 4-Disubstituted 1, 2, 3-Triazoles from 1, 1-Dibromoalkenes

Su Changhui ¹ ,
Liu Xia ^2,, ,
Pan Tao ² ,
Shen Hong ² ,
Hang Zhaoqin ²

1.
School of Chemistry and Life Science, Nanjing University Jinling College, Nanjing 210089
2.
College of Environment Science and Ecology, Jiangsu Open University, Nanjing 210036

Corresponding author: Liu Xia, liuxia_1107@163.com
Received Date: 16 July 2019
Accepted Date: 26 September 2019

Figures(3)

1, 4-Disubstituted 1, 2, 3-triazoles were synthesized by a CuI catalyzed one-pot reaction using 1, 1-dibromoalkenes and aryl azides as raw materials under room temperature. The structures of target compounds were characterized by IR, MS, ¹H NMR and ¹³C NMR spectroscopy. Effects of the amount of catalyst, solvent and the reaction temperature on the yields of product were studied, and the possible reaction mechanism was proposed. This method has the advantages of environment friendly, mild reaction conditions, simple one pot operation and high yield.
- 1, 1-Dibromoalkene,
- One-pot synthesis,
- 2, 3-Triazoles,
- Heterocycles
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