Citation: Tang Siyu, Qi Yayun, Hu Weinan, Chen Jie, Zhu Mei, Shao Lihui, Wang Zhenchao, Ouyang Guiping. Progress in Syntheses and Biological Activities of[1,2,4]Triazolo[3,4-b] [1,3,4]thiadiazine Derivatives[J]. Chemistry, ;2020, 83(6): 529-535. shu

Progress in Syntheses and Biological Activities of[1,2,4]Triazolo[3,4-b] [1,3,4]thiadiazine Derivatives

Tang Siyu ¹ ,
Qi Yayun ¹ ,
Hu Weinan ¹ ,
Chen Jie ¹ ,
Zhu Mei ¹ ,
Shao Lihui ¹ ,
Wang Zhenchao ^1,2,, ,
Ouyang Guiping ^1,2,3,,

1.
School of Pharmacy, Guizhou University, Guiyang, 550025
2.
State Key Laboratory of Functions and Application of Medicinal Plants, Guizhou Medicinal University, Guiyang, 550014
3.
Guizhou Engineering Laboratory for Synthetic Drugs, Guiyang, 550025

Corresponding author: Wang Zhenchao, wzc.4884@163.com Ouyang Guiping, oygp710@163.com
Received Date: 16 December 2019
Accepted Date: 2 January 2020

Figures(6)

The[1,2,4]triazolo[3,4-b] [1,3,4]thiadiazine as a promising active group has received extensive attention because of its pharmacological activities in antibacterial, anti-tumor and other aspects in the field of medicine and chemistry. In this paper, based on the syntheses of compounds containing triazolidazide structure and their anti-tumor, antibacterial and other activities in recent years, the research on[1,2,4] triazolazine[3,4-b] [1,3,4] thiadiazine compounds was analyzed and summarized, so as to provide reference for the design and synthesis of these novel antitumor compounds.
- [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazine,
- Antitumor,
- Antibacterial activity
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