Citation: Liu Shizhao, Abudu Rexit·Abulikemu. A Simple, Mild, Efficient and Metal-Free Synthesis Method of Disulfides[J]. Chemistry, ;2019, 82(3): 270-274. shu

A Simple, Mild, Efficient and Metal-Free Synthesis Method of Disulfides

Liu Shizhao ,
Abudu Rexit·Abulikemu ^,

Department of Chemistry, College of Chemistry and Chemical Engineering, Xinjiang Normal University, Urumqi 830054

Corresponding author: Abudu Rexit·Abulikemu, aarexit@xjnu.edu.cn
Received Date: 15 October 2018
Accepted Date: 16 November 2018

In this paper, thiophenols or mercaptans were self-coupled to form bisulfide in the presence of tribromophenone with 95% ethanol as solvent, which provided a mild, simple, green and metal-free synthesis method after traditional methods. A variety of thiophenols and mercaptans were investigated under the optimum reaction conditions. It was found that aromatic hydrocarbons containing electron withdrawing groups could obtain higher yields than that with electron-withdrawing groups, and the reaction time was also shorter. At the same time, the substrates of aliphatic and heterocyclic compounds also had relatively higher yields in this reaction.
- Disulfides,
- α, α-three bromoacetophenone,
- Free radical reaction
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