Citation: Cui Hua XUE, Qi Ming MU, Shu Hua CHEN. Design and Synthesis of Chiral Molecular Tweezers Based on Deoxycholic Acid[J]. Chinese Chemical Letters, ;2001, 12(5): 413-416. shu

Design and Synthesis of Chiral Molecular Tweezers Based on Deoxycholic Acid

The Faculty of chemistry, Sichuan University, Chengdu 610064

Received Date: 1 November 2000

Fund Project: We are very grateful to the National Natural Science Foundation of China (project:No.29772024) for the financial support.

A series of new chiral molecular tweezers have been designed and synthesized by using deoxycholic acid as spacer and aromatic amines as arms.Instead of using toxic phosgene,the triphosgene was employed in synthesis of the molecular tweezers receptors.These chiral molecular tweezers showed good enantioselectivity for D-amino acid methyl esters.
- Molecular tweezers,
- synthesis,
- deoxycholic acid,
- recognition.
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