Citation: Guo Wei, Cai Zhaosheng, Xu Qi. Progress in Preparation and Application of Hydroxyalkyl Chitosan[J]. Chemistry, ;2019, 82(4): 299-309. shu

Progress in Preparation and Application of Hydroxyalkyl Chitosan

Guo Wei ^1,2 ,
Cai Zhaosheng ^2,, ,
Xu Qi ²

1.
School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212000
2.
School of Chemistry and Chemical Engineering, Yancheng Institute of Technology, Yancheng 224000

Corresponding author: Cai Zhaosheng, jsyc_czs@163.com
Received Date: 11 October 2018
Accepted Date: 11 December 2018

Figures(10)

Chitosan is a high-molecular polysaccharide obtained by deacetylation of chitin, which has good biocompatibility, antibacterial activity and the advantages of being non-toxic and biodegradable. However, the poor water solubility of chitosan limits its application in many aspects. In order to overcome this shortage, the chemical modification for chitosan to introduce hydrophilic groups into the amino group and hydroxyl group of chitosan have became important methods. In this paper, different chitosan hydroxyalkylation methods are discussed. Meanwhile, the applications about the hydroxyalkyl chitosan and their derivatives in medicine, water treatment and tissue engineering materials are presented, and the future development trend of hydroxyalkyl chitosan is prospected.
- Chitosan,
- Tissue engineering materials,
- Water-solubility,
- Water treatment
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