Citation: Chu Xiangyu, Wang Xiaoyong. Effect of Zein/Tween-20 Composite Nanoparticles on the Properties of Encapsulated Curcumin[J]. Chemistry, ;2018, 81(7): 625-629. shu

Effect of Zein/Tween-20 Composite Nanoparticles on the Properties of Encapsulated Curcumin

Chu Xiangyu ,
Wang Xiaoyong ^,

School of Chemistry & Molecular Engineering, East China University of Science and Technology, Shanghai 200237

Corresponding author: Wang Xiaoyong, xiaoyong@ecust.edu.cn
Received Date: 1 April 2018
Accepted Date: 7 May 2018

Figures(5)

In this paper, zein/Tween-20 composite nanoparticles were prepared by anti-solvent precipitation. By measuring the encapsulation efficiency, stability, and fluorescence properties of curcumin in zein/Tween-20 composite nanoparticles, the influence of Tween-20 concentration on the interaction between zein/Tween-20 composite nanoparticles and curcumin was investigated. Compared to zein nanoparticles, zein/Tween-20 composite nanoparticles can significantly increase the encapsulation efficiency, stability, fluorescence emission intensity, and anisotropy of curcumin. These results indicate that curcumin is bound in hydrophobic domains of zein/Tween-20 composite nanoparticles via hydrophobic interactions. Tween-20 as a stabilizer not only helps to produce smaller zein/Tween-20 composite nanoparticles, but also provides a more suitable hydrophobic binding environment for curcumin.
- Zein,
- Tween-20,
- Curcumin,
- Encapsulation efficiency,
- Stability,
- Fluorescence
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