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Citation: Wang Xuezhi, Zhang Ji'min, Qin Honggui. Synthesis,Characterization and Antitumor Activity of Polynuclear Solid Complex of Lanthanum with Dithiocarbaminoacetic Cobalt[J]. Chinese Journal of Applied Chemistry, ;1998, 15(3): 39-42. shu

Synthesis,Characterization and Antitumor Activity of Polynuclear Solid Complex of Lanthanum with Dithiocarbaminoacetic Cobalt

1.
Department of Biochemical Engineering, Anhui Institute of Mechanical and Electrical Engineering, Wuhu 241000;
2.
Department of Inspection, Yijishan Hospital of Wannan Medical College, Wuhu 241000

Received Date: 24 November 1997
Revised Date: 20 March 1998

The new polynuclear solid complex of lanthanum(La) with dithiocarbaminoacetic cobalt [Co(HL)₂](L=^-S₂CNHCH₂CO₂^-) was synthesized in microwave oven at 60 ℃. The product was characterized by elemental analysis, IR spectrum, UV absorption spectrum, ¹H NMR and molar conductance measurements. The results showed that the composition of the complex was La₂(CoL₂)₃. The preliminary bioassay showed that the complex could significantly inhibit the growth of liver cancer cell, but not affect on the growth of human liver cells.
- lanthanum,
- dithiocarbaminoacetic cobalt,
- polynuclear complex,
- antitumor activity
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