Citation: Ding Xuguang, Yu Haifeng, Zhao Hui, Yang Yong. Cyclization of α-Diaryl methyl-β-ketothioesters and Hydrazine: Synthesis of Functionalized 5-Hydroxy Pyrazolyl-Containing Triarylmethanes[J]. Chemistry, ;2017, 80(12): 1152-1155, 1127. shu

Cyclization of α-Diaryl methyl-β-ketothioesters and Hydrazine: Synthesis of Functionalized 5-Hydroxy Pyrazolyl-Containing Triarylmethanes

School of Chemistry and Life Science, Anshan Normal University, Anshan 114007

Corresponding author: Yu Haifeng, yuhf68105@sina.com
Received Date: 30 May 2017
Accepted Date: 12 September 2017

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We developed the cyclization reactions of α-diaryl methyl-β-ketothioesters and hydrazine for the synthesis of functionalized 5-hydroxy pyrazolyl-containing triarylmethanes. The cyclization reactions of α-diaryl methyl-β-ketothioesters and hydrazine were performed in refluxing EtOH, affording functionalized 5-hydroxy pyrazolyl-containing triarylmethanes in excellent yield. Mild reaction conditions, easy work-up procedure, and excellent yields are some notable advantages of this method.
- Thioester,
- Triarylmethane,
- Cyclization reaction,
- 5-Hydroxy pyrazole
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