Citation: Sun Mengxue, Yu Chanchan, Xu Min, Feng Xueyan, Yao Li. Advances in DNA Mechanical Technology[J]. Chemistry, ;2020, 83(10): 866-874, 918. shu

Advances in DNA Mechanical Technology

Sun Mengxue ^1,2 ,
Yu Chanchan ^1,2 ,
Xu Min ^1,2 ,
Feng Xueyan ^1,2 ,
Yao Li ^1,2,,

1.
Beijing National Laboratory for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, Chinese Academy of Science, Beijing, 100190
2.
University of Chinese Academy of Sciences, Beijing, 100049

Corresponding author: Yao Li, yaoli@iccas.ac.cn
Received Date: 15 June 2020
Accepted Date: 14 July 2020

Figures(6)

DNA mechanical technology has been widely concerned and deeply studied in recent years. Mechanical DNA devices have been enabled by the unique molecular structure and physical and chemical properties of DNA. More complex mechanical behavior or function can be achieved by designing more elaborate mechanisms. DNA mechanical technology has played important role in studies of the fundamental properties of the biomolecules that sense, transmit, and generate pN forces. Studies of the mechanics of these biomolecules are essential to revealing their functions. Here, we reviewed the latest progress in the study of DNA mechanical technology. First, the mechanical basis of DNA was briefly described. Especially several types of mechanical DNA devices were focused on. Finally, the challenges and prospects of DNA mechanical technology were discussed.
- DNA mechanical technology,
- Molecular machine,
- Sensor,
- Molecular Interaction
1. [1]
  Seeman N C. J. Theor. Biol., 1982, 99: 237-247.
2. [2]
  Luo D. Mater. Today, 2003, 6: 38-43.
3. [3]
  LaBean T H, Li H Y. Nano Today, 2007, 2: 26-35.
4. [4]
  Seeman N C. Nature, 2003, 421: 427-431.
5. [5]
  Seeman N C, Lukeman P S. Rep. Prog. Phys., 2005, 68: 237-270.
6. [6]
  Lin C, Liu Y, Yan H. Biochemistry, 2009, 48: 1663-1674.
7. [7]
  Feldkamp U, Niemeyer C M. Angew. Chem. Int. Ed., 2006, 45: 1856-1876.
8. [8]
  Blanchard A T, Bazrafshan A S, Yi J, et al. Nano Lett., 2019, 19: 6977-6986.
9. [9]
  Neuman K C, Nagy A. Nat. Methods, 2008, 5: 491-505.
10. [10]
  Kilchherr F, Wachauf C, Pelz B, et al. Science, 2016, 353: aaf5508.
11. [11]
  Han D, Pal S, Nangreave J, et al. Science, 2011, 332: 342-346.
12. [12]
  Langecker M, Arnaut V, Martin T G, et al. Science, 2012, 338: 932-936.
13. [13]
  Douglas S M, Bachelet I, Church G M. Science, 2012, 335: 831-834.
14. [14]
  Douglas S M, Chou J J, Shih W M. PNAS, 2007, 104: 6644-6648.
15. [15]
  Ding B, Deng Z, Yan H, et al. J. Am. Chem. Soc., 2010, 132: 3248-3258.
16. [16]
  Maune H T, Han S, Barish R D, et al. Nat. Nanotechnol., 2010, 5: 61-66.
17. [17]
  Derr N D, Goodman B S, Jungmann R, et al. Science, 2012, 338: 662-665.
18. [18]
  Tinland B, Pluen A, Sturm J, et al. Macromolecules, 1997, 30: 5763-5765.
19. [19]
  Yang D, Campolongo M J, Tran T N N, et al. DNA materials and their applications. Wiley Interdiscip. Rev-Nanomed Nanobiotechnol., 2010, 2: 648-669.
20. [20]
  Zhang K, Zhu X, Jia F, et al. J. Am. Chem. Soc., 2013, 135: 14102-14105.
21. [21]
  Amodio A, Adedeji A F, Castronovo M, et al. J. Am. Chem. Soc., 2016, 138: 12735-12738.
22. [22]
  Zhu B, Zhao Y, Dai J B, et al. ACS Appl. Mater. Interf., 2017, 9: 18434-18439.
23. [23]
  Surana S, Shenoy A R, Krishnan Y. Nat. Nanotechnol., 2015, 10: 741-747.
24. [24]
  Zhu G, Zheng J, Song E, et al. PNAS, 2013, 110: 7998-8003.
25. [25]
  Xie N, Huang J, Yang X, et al. Chem. Commun., 2016, 52: 2346-2349.
26. [26]
  Niemeyer C M, Ceyhan B, Hazarika P. Angew. Chem. Int. Ed., 2003, 42: 5766-5770.
27. [27]
  Nickels P C, Wunsch B, Holzmeister P, et al. Science, 2016, 354: 305-307.
28. [28]
  Holliday R. Genet. Res., 1964, 5: 282-290.
29. [29]
  Meselson M S, Radding C M. PNAS, 1975, 72: 358-361.
30. [30]
  Lin C X, Liu Y, Rinker S, et al. Chem. Phys. Chem., 2006, 7: 1641-1647.
31. [31]
  Winfree E, Liu F R, Wenzler L A, et al. Nature, 1998, 394: 539-544.
32. [32]
  Fu T J, Seeman N C. Biochemistry, 1993, 32: 3211-3220.
33. [33]
  Li X J, Yang X P, Qi J, et al. J. Am. Chem. Soc., 1996, 118: 6131-6140.
34. [34]
  Liu F R, Sha R J, Seeman N C. J. Am. Chem. Soc., 1999, 121: 917-922.
35. [35]
  Reishus D, Shaw B, Brun Y, et al. J. Am. Chem. Soc., 2005, 127: 17590-17591.
36. [36]
  LaBean T H, Yan H, Kopatsch J, et al. J. Am. Chem. Soc., 2000, 122: 1848-1860.
37. [37]
  Liu Y, Lin C X, Li H Y, et al. Angew. Chem. Int. Ed., 2005, 44: 4333-4338.
38. [38]
  Liu D, Park S H, Reif J H, et al. PNAS, 2004, 101: 717-722.
39. [39]
  Yan H, Zhang X P, Shen Z Y, et al. Nature, 2002, 415: 62-65.
40. [40]
  Shen Z Y, Yan H, Wang T, et al. J. Am. Chem. Soc., 2004, 126: 1666-1674.
41. [41]
  Liu W Y, Wang X, Wang T, et al. Nano Lett., 2008, 8: 317-322.
42. [42]
  Rothemund P W. Nature, 2006, 440: 297-302.
43. [43]
  ChaoY C, Hong Y J, Lee C Y, et al. Nanoscale, 2020, 12: 2992-2998.
44. [44]
  Shin J S, Pierce N A. J. Am. Chem. Soc., 2004, 126: 10834-10835.
45. [45]
  Gu H, Chao J, Xiao S J, et al. Nature, 2010, 465: 202-205.
46. [46]
  Lund K, Manzo A J, Dabby N, et al. Nature, 2010, 465: 206-210.
47. [47]
  Wickham S F, Bath J, Katsuda Y, et al. Nat. Nanotechnol., 2012, 7: 169-173.
48. [48]
  Yang Y, Goetzfried M A, Hidaka K, et al. Nano Lett., 2015, 15: 6672-6676.
49. [49]
  Liber M, Tomov T E, Tsukanov R, et al. Small, 2015, 11: 568-575.
50. [50]
  Thubagere A J, Li W, Johnson R F, et al. Science, 2017, 357: eaan6558.
51. [51]
  Li S P, Jiang Q, Liu S L, et al. Nat. Biotechnol., 2018, 36: 258-261.
52. [52]
  Evans E A, Calderwood D A. Science, 2007, 316: 1148-1153.
53. [53]
  Levental K R, Yu H, Kass L, et al. Cell, 2009, 139: 891-906.
54. [54]
  Kim S T, Takeuchi K, Sun Z Y, et al. J. Biol. Chem., 2009, 284: 31028-31037.
55. [55]
  Qiu Y, Brown A C, Myers D R, et al. PNAS, 2014, 111: 14430-14435.
56. [56]
  Kanchanawong P, G Shtengel, Pasapera A M, et al. Nature, 2010, 468: 580-U262.
57. [57]
  Schwarz U S, Soine J R D. Biochim. Biophys. Acta-Mol. Cell Res., 2015, 1853: 3095-3104.
58. [58]
  Blakely B L, Dumelin C E, Trappmann B, et al. Nat. Methods, 2014, 11: 1229-1241.
59. [59]
  KongF, García A J, Mould A P, et al. J. Cell Biol., 2009, 185: 1275-1284.
60. [60]
  Liu Y, Blanchfield L, Ma V P, et al. PNAS, 2016, 113: 5610-5615.
61. [61]
  Dutta P K, Zhang Y, Blanchard A T, et al. Nano Lett., 2018, 18: 4803-4811.
62. [62]
  Ma R, Kellner A V, Ma V P Y, et al. PNAS, 2019, 116: 16949-16954.
63. [63]
  Yao L, Li Y, W T Tsai, et al. Angew. Chem. Int. Ed., 2013, 52: 14041-14044.
64. [64]
  Lu P, Zhang D, Chai Y H, et al. Anal. Chim. Acta, 2019, 1045: 1-9.
65. [65]
  Brockman J M, Blanchard A T, Ma V P, et al. Nat. Methods, 2018, 15: 115-117.
66. [66]
  Zhao Y C, Sarkar A, Wang X F. Biosens. Bioelectron., 2020, 150: 111959.
67. [67]
  Yurke B, Turberfield A J, Mills A P, et al. Nature, 2000, 406: 605-608.
68. [68]
  Powell J T, Akhuetie-Oni B O, Zhang Z, et al. Angew. Chem. Int. Ed., 2016, 55: 11412-11416.
69. [69]
  Kuzuya A, Sakai Y, Yamazaki T, et al. Nat. Commun., 2011, 2: 449.
70. [70]
  Marras A E, Zhou L, Su H J, et al. PNAS, 2015, 112: 713-718.
71. [71]
  Ketterer P, Willner E M, Dietz H, et al. Sci. Adv., 2016, 2: e1501209.
72. [72]
  Ke Y, Meyer T, Shih W M, et al. Nat. Commun., 2016, 7: 10935.
73. [73]
  Gerling T, Kube M, Kick B et al. Sci. Adv., 2018, 4: eaau1157.
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