Citation: Yuan MA, Xiang Hong LI, Yi CHEN, Yu Ping FENG, Yu Fen ZHAO. Formation of Dithymidylic Acid by Ester Exchange Reaction on N-Phosphoryl Serine[J]. Chinese Chemical Letters, ;1996, 7(10): 905-906. shu

Formation of Dithymidylic Acid by Ester Exchange Reaction on N-Phosphoryl Serine

a Department of Chemistry Bio-organic Phosphorus Chemistry Laboratory School of Life Science and Engineering Tsinghua University Beijing 100084;
b Institute of Chemistry Chinese Academy of Sciences Beijing 100080

Received Date: 22 April 1996

Fund Project: The project was supported by the National Natural Science Foundation of China, the Chinese National Education Ministry and the National Science and Technology Committee.

Ester exchange reaction between the thymidine and N-(O, O-diisopropyl)phosphoryl serine could yield several derivatives of thymidylic acid, including dithymidylic acid.These results might be meaningful to the prebiotic synthesis of macromolecules.
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